Slightly high blood uric acid? Do you understand these things?

With the continuous improvement of dietary standards, many people will suffer from high uric acid and high blood uric acid due to irregular and uncontrolled diet. High blood uric acid can cause other complications in the body and greatly affect health. So many people have heard of high uric acid. What is the cause of high blood uric acid? What harm will it cause to the body?

Cause

What are the causes of high blood uric acid? This is a question that many patients with high blood uric acid do not understand but want to know. In fact, high blood uric acid is a very common kidney disease. There are only three reasons for the increase in blood uric acid levels. So what are the three reasons?

1. Excessive production of high blood uric acid

Excessive purine intake: High blood uric acid levels are directly proportional to the purine content in food. 50% of RNA and 25% of DNA in the food consumed are excreted in the urine in the form of uric acid. Strictly limiting purine intake can reduce serum uric acid levels to 60umol/L (1.0mg/dL) and urinary uric acid secretion to 1.2mmol/d (200mg/d).

Excessive production of endogenous purines: A: Causes

Because the main use of purine is as a component of DNA and RNA, when cellular RNA and DNA are oxidized and decomposed too much and synthesis is reduced, a large amount of DNA and RNA fragments will be produced, which means more purine is produced. When cells are oxidized, the first thing to be damaged is DNA. Therefore, the older people are, the more purine they produce, and the higher the proportion of gout. The right picture shows: The more DNA is broken down into fragments, the more purine it naturally produces, which is the main source of endogenous uric acid.

B: Reason

The de novo synthesis of purine from non-cyclic to cyclic forms requires 11 steps, during which abnormalities in the enzymes can lead to excessive purine synthesis.

Precautions

1. Try to maintain your body weight within the ideal range. If you need to lose weight, do it slowly, because rapid weight loss will cause tissue to decompose faster, which will in turn cause the production of a large amount of uric acid.

2. The diet should be mainly vegetarian, eat less animal oil as much as possible, and use steaming, boiling, and cold cooking methods more often, which can have a good effect on lowering blood uric acid.

3. Choose more foods rich in vitamin B1 and vitamin C, such as rice, noodles, milk, eggs, fruits and various vegetable oils.

General matters

The intake of animal offal, fish skin and seafood, dried beans and nuts, various broths, and some vegetables (agaragar, celery, cauliflower, spinach), etc. should be strictly controlled. Drink plenty of water, because adequate water can help uric acid be excreted smoothly. Drink less alcohol, because alcohol is metabolized into lactic acid in the human body, which affects the excretion of uric acid.