How to treat herpes coronary artery? You should relieve this!

Coronary herpes is a common type of genital herpes, which is caused by a viral infection. This disease can cause great pain to male patients, and it will relapse if not treated thoroughly, affecting the couple's sex life. So how should it be treated?

1. Local therapy:

The principle is to dry, astringe, and protect the affected area to prevent secondary infection. You can apply 2% gentian violet solution, or 10% bismuth subgallate (dermatol), zinc oxide ointment or mud, lithospermum parkii ointment, 0.5% neomycin ointment, or 0.25%~0.1% IDU ointment, 5% IDU dimethyl sulfoxide solution (for skin herpes), etc. For the face, 10% aluminum acetate or zinc-copper mixture can also be used.

2. Systemic treatment:

The first principle of treatment is to prevent the activation of infected HSV or even eliminate the virus; the second is to regulate immunity and prevent recurrence. Acyclovir can be taken intravenously or orally, Livzonvir can be taken orally, interferon can be injected intramuscularly, and interleukin II can be injected intramuscularly. When we treat recurrent genital herpes, we use 3 million units of interferon produced by the Biotechnology Center of the Fourth Medical University for intramuscular injection, once a day, 10 times as a course of treatment, for a total of three courses, and appropriately use interleukin II, Levitra or Bactrobactin, and 95% of patients do not relapse.

3. Pathogen therapy

(1) Acyclovir (acyclovir): It can selectively inhibit viral replication, reduce the occurrence of new lesions, relieve pain, shorten wound healing and detoxification time. For primary or initial GH, 0.2g, orally, 5 times/d, for 7 to 10 days; for recurrent GH, 0.2g, orally, 5 times/d, for 5 days, or 0.4g, orally, 3 times/d, for 5 days, or 0.8g, orally, 2 times/d, for 5 days. For mild patients, 1 to 1.6g/d, divided into 5 oral doses, for 5 to 7 days; for severe patients, 15mg/(kg·d), intravenous injection, for 5 to 7 days. Use with caution in patients with dehydration and renal insufficiency. In recent years, acyclovir (ACV) derivatives such as valacyclovir and famciclovir have also been used to treat this disease.

(2) Sodium foscarnet: For patients with TK gene defects who are resistant to ACV virus infection, 40 mg/kg of sodium foscarnet can be used by intravenous injection once every 8 hours until recovery.

(3) Ribavirin (ribavirin): 0.6-0.8 g/d, orally or intramuscularly, for 5-7 days.

(4) α, β and γ-interferon (α, β, γ-IFN): 1 million u/d for 5 to 7 days.

(5) 2-4 ml of poly I-cell is injected intramuscularly once every other day for 5-7 days.

(6) Cytarabine and the like can also be used.

4. Immunotherapy

Straus et al. used gD-2 vaccination, which is glycoprotein D of recombinant HSV-2 expressed in CHO cells, to induce antigen-specific neutralizing antibodies equivalent to or exceeding the level produced by GH patients. The vaccination was 100 μg/time, repeated once after 2 months. Compared with the control group, the number of relapses was significantly reduced, and it was also effective in alleviating symptoms and preventing infection.

5. Topical Therapy

Care should be taken to protect the wound surface, keep it clean and dry, and prevent secondary bacterial infection. 5% acyclovir (ACV) ointment or emulsion, α or β interferon emulsion or gel, 1% gentian violet solution, 3% tetracycline ointment or 25% zinc oxide oil can be used.