What medicine is better for irritable bowel syndrome

When it comes to the treatment of irritable bowel syndrome, drug therapy is relatively common, but the choice of drugs certainly cannot be blind. The use of nifedipine, pinaverium bromide or some laxatives are all necessary drug treatments.

(1) Gastrointestinal antispasmodics Anticholesterol drugs are the most commonly used. They can also partially antagonize the gastrocolic reflex and reduce intestinal gas production, thereby alleviating postprandial abdominal pain. Calcium channel blockers include nifedipine (nifedipine) and pinaverium bromide.

(2) Gastrointestinal motility-related drugs: loperamide, domperidone (Metoclopramide), cisapride, etc.

(3) Laxatives are usually avoided, but they can be used for a short period of time for those with severe constipation. Hemicellulose or osmotic laxatives are preferred. Taking 15 to 30 ml of lactulose before bedtime is also effective, especially for the elderly.

(4) Psychotropic drugs: For patients with obvious psychiatric symptoms, appropriate administration of sedatives, antidepressants, and antianxiety drugs can be helpful.

(5) To eliminate gastrointestinal bloating, dimethicone and medicinal charcoal (activated carbon) have the effect of removing gas and foaming, and are commonly used in clinical practice.

(6) Intestinal probiotics Some patients with diarrhea may have intestinal flora disorders, and the use of intestinal probiotic preparations can be helpful.

(7) Other 5-HT4 receptor partial agonists such as tegaserod are effective for constipation-type IBS and can significantly improve patients' abdominal pain symptoms. The 5-HT3 receptor antagonist alosetron is effective for diarrhea-predominant IBS.