What harm does uremia do to the body?

I believe many of my friends are very clear about the importance of kidneys to the human body. If some kidney diseases are not treated in time, the harm of developing into uremia in the later stage will be more serious. However, some friends are not particularly clear about the harm of uremia, and do not know how serious the harmfulness of this disease is. Therefore, this article will analyze the harm of uremia to the body for you friends.

The early hazards of uremia are not invisible. In the period of chronic uremia, in addition to the further aggravation of electrolyte and acid-base imbalance, anemia, bleeding tendency, hypertension, etc., there will also be clinical manifestations caused by material metabolic disorders such as dysfunction of various organ systems.

First, nervous system diseases are the main symptoms of chronic uremia. In the early stages of chronic uremia, patients often suffer from symptoms such as dizziness, headache, fatigue, and decreased consciousness and memory. As the disease worsens, patients may experience restlessness, muscle tremors, and convulsions; finally, they may develop into apathy, drowsiness, and coma.

Second, the earliest symptom of the digestive system in patients with uremia is loss of appetite or indigestion; when the condition worsens, anorexia, nausea, vomiting or diarrhea may occur. The onset of these symptoms may be related to the fact that urease from intestinal bacteria synthesizes urea into ammonia, which stimulates the gastrointestinal mucosa, causing inflammation and multiple superficial ulcers. Patients often have gastrointestinal bleeding. In addition, nausea and vomiting are also related to dysfunction of the central nervous system.

Third, patients with chronic renal failure may suffer from heart failure, arrhythmia and myocardial damage due to the effects of renal hypertension, acidosis, hyperkalemia, sodium and water retention, anemia and toxic substances. Due to the irritation of urea (and possibly uric acid), sterile pericarditis may also occur, with the patient experiencing precordial pain and a pericardial friction sound during physical examination. In severe cases, fibrin and bloody exudates are present in the pericardial cavity.

Fourth, skin itching is a common symptom in patients with chronic uremia, which may be caused by the stimulation of skin receptors by toxic products; some people believe that it is related to secondary hyperparathyroidism, because this painful symptom can be immediately relieved after parathyroid removal. In addition, the patient's skin becomes dry, flaky, and yellow-brown.

This article has introduced very clearly the harm of uremia to the body. Here I would also like to remind all friends that uremia is an incurable disease. Even if the kidney is replaced, there will be many risks. For this reason, the most critical issue is to prevent uremia and prevent ourselves from getting this disease. I also hope that kidney patients will pay enough attention to uremia.