What's the matter with the low neutrophil ratio

When looking at the routine blood test report, what the doctor needs to pay special attention to is the neutrophil ratio. Whether it is too high or too low, it means that the patient has an inflammatory infection, but there is an essential difference between being too low and too high. However, many friends know what a high neutrophil ratio means, but they don’t know what a low neutrophil ratio means. So let’s learn about it here.

Neutrophils are a type of white blood cell and also a type of immune cell in the body. When there is an inflammatory infection, the body will be stimulated to produce a large number of neutrophils to kill pathogens and fight the inflammatory infection. Reduction is generally seen in infectious diseases such as typhoid, paratyphoid, measles, influenza, chemotherapy, and radiotherapy. Certain blood diseases (plastic anemia, agranulocytosis, myelodysplastic syndrome), hypersplenism, autoimmune diseases, etc.

There are several common reasons for low neutrophil count:

1. Infection, especially bacillus infection. Some viral infections may also be low, such as influenza, viral hepatitis, etc.

2. Blood system diseases, such as aplastic anemia, malignant tumors, etc.

3. Damage caused by physical and chemical factors, such as X-rays, anti-tumor drugs, etc.

4. Hyperfunction of the mononuclear phagocyte system, such as hypersplenism.

5. Autoimmune diseases, such as systemic lupus erythematosus.

The low rate is caused by infection. Recheck blood routine test after infection is under control. It is better to use antibiotics to control the infection. You can do a drug sensitivity test and use targeted medication.

The cell membrane of neutrophils can release an unsaturated fatty acid - arachidonic acid, which, under the action of enzymes, further produces a group of paracrine hormone substances, such as thromboxane and prostaglandins. These substances have a significant effect on regulating blood vessel caliber and permeability, can also cause inflammatory reactions and pain, and affect blood coagulation.

After understanding what causes a low neutrophil ratio, please do not worry too much. Although the causes of a low neutrophil ratio are complicated, it is also possible that this situation is simply caused by a viral infection. If this is the case, you only need to undergo simple antiviral treatment.