What is ichthyosis variegated and how to prevent it

Do you know of a disease? . It is called ichthyosis variegated, a terrible disease, and it is almost impossible to completely eradicate it if you are infected with it. It is a congenital disease, and in my eyes it is a terrible disease. But I still want to remind patients not to worry about ichthyosis maculata. I will tell you how to prevent it and teach you how to maintain it. Don't be afraid, learn to have a positive attitude.

The main cause of HI is the mutation of the ABCA gene at site 2q34, which leads to abnormalities in the ABCA12 protein that regulates lipid transport. The skin epidermis can be divided into 5 layers, and the outermost layer of the stratum corneum is composed of dead keratin cells. The lamella granules of HI patients' keratinocytes lack or have abnormal ABCA12 protein, which causes the stratum corneum to lose lipids and the skin's desquamation process to fail, resulting in a large accumulation of keratin and abnormal skin permeability. These large-scale, angular, compact keratin patches will pull deep tissues on the skin and produce cracked scars. These gray armor-like keratin blocks also cause abnormal tightening of the eyes, mouth, ears and limbs, destroying the protection and defense of the skin, causing an imbalance in the regulation of water and body temperature, and often leading to serious bacterial infections.

Here are some treatment methods for patients:

1. General treatment:

1. Bathe frequently with warm water and apply appropriate amount of skin care oil.

2. Keep warm in winter.

3. Eat more fruits and vegetables.

2. Western medicine treatment:

1. Oral administration: Take large doses of vitamin A, 100,000-300,000 u per day or vitamin A acid, 1 mg/kg per day. However, long-term use may cause bone calcium, hair loss and other symptoms of poisoning.

2. External use of 10% urea cream, 0.1% vitamin A acid cream or 2% cod liver oil ointment can help relieve dry skin, desquamation and cracking.

I believe everyone knows that trouble comes from the mouth. We should wash our hands, take a shower, change clothes frequently... and basically start with ourselves. Ichthyosis variegated is not scary. The scariest thing is that you cannot face it. The biggest enemy in the world is yourself. As long as you think it through and see it clearly, it will be easy to solve. There is nothing to be afraid of ichthyosis variegata. Believe in yourself and keep going!