Is malignant hydatidiform mole hereditary?

Malignant hydatidiform mole is not a hereditary disease. Its occurrence is mainly related to the abnormal development of the fertilized egg. Treatments include surgical curettage, chemotherapy, and monitoring and follow-up. Malignant hydatidiform mole is caused by abnormalities in the development of the fertilized egg, which leads to excessive proliferation of placental villous cells and the formation of grape-like blister structures. This abnormality is usually related to factors such as maternal age, previous history of hydatidiform mole, and nutritional status, rather than genetic factors.

1. The cause of malignant hydatidiform mole is mainly related to abnormal fertilized eggs. During the fertilization process, abnormalities in the chromosomes of the egg or sperm may lead to abnormal development of the fertilized egg, which in turn leads to hydatidiform mole. Older mothers, a history of hydatidiform mole, malnutrition or vitamin A deficiency may increase the risk of disease. Environmental factors such as long-term exposure to chemicals or radiation may also have adverse effects on the development of fertilized eggs.

2. The diagnosis of malignant hydatidiform mole mainly relies on ultrasound examination and serum hCG level detection. Ultrasound examination can reveal grape-like vesicular structures in the uterus, and serum hCG levels are usually significantly elevated. After the diagnosis is confirmed, uterine curettage should be performed as soon as possible to completely remove abnormal tissues to avoid further deterioration of the condition.

3. Uterine curettage is the preferred method for treating malignant hydatidiform mole. Abnormal tissue in the uterus can be effectively removed by curettage or aspiration. Serum hCG levels should be closely monitored after surgery to ensure that they gradually drop to the normal range. If hCG levels continue to rise or drop slowly, it may indicate that the condition is not completely controlled and further treatment is required.

4. Chemotherapy is an important treatment for malignant hydatidiform mole. For high-risk patients or patients whose hCG levels continue to rise after surgery, chemotherapy is required to kill the remaining abnormal cells. Commonly used chemotherapy drugs include methotrexate, actinomycin D, etc. The specific plan needs to be determined according to the patient's condition and the doctor's advice.

5. Patients with malignant hydatidiform mole need long-term follow-up. After surgery and chemotherapy, serum hCG levels and ultrasound examinations should be regularly reviewed to monitor changes in the condition. During the follow-up period, patients should maintain good living habits and avoid getting pregnant again until the doctor confirms that the condition is completely under control.

The treatment of malignant hydatidiform mole requires a combination of surgery, chemotherapy, and follow-up. Patients should actively cooperate with doctors for treatment and undergo regular checkups to ensure that the condition is effectively controlled. At the same time, maintaining good living habits and nutritional status can help reduce the risk of disease.