Which is the first choice for the treatment of hydatidiform mole

The first choice for the treatment of hydatidiform mole is uterine curettage, which can completely remove abnormal tissue and avoid complications. Drug therapy and hysterectomy are also options, but they need to be selected according to the specific situation of the patient. Hydatidiform mole is a disease caused by abnormal development of the fertilized egg, which is manifested by abnormal proliferation of placental villi and the formation of grape-like blisters, which may cause severe consequences such as heavy bleeding and malignant transformation.

1. Uterine curettage is the preferred treatment for hydatidiform mole. Abnormal tissue in the uterine cavity is removed by vacuum suction or curettage. The operation is simple and effective. Blood HCG levels should be closely monitored after surgery to ensure complete removal. For partial hydatidiform mole, the risk of malignant transformation after uterine curettage is low, but for complete hydatidiform mole, it is necessary to be vigilant against malignant transformation into invasive hydatidiform mole or choriocarcinoma.

2. Drug treatment is suitable for patients with mild disease who have fertility needs. Commonly used drugs include methotrexate and actinomycin D. These drugs can inhibit the proliferation of trophoblasts and promote the absorption of abnormal tissues. However, the drug treatment cycle is long, and regular monitoring of blood HCG and ultrasound examinations are required to evaluate the treatment effect. If drug treatment is ineffective or the condition worsens, surgery should still be considered.

3. Hysterectomy is suitable for patients who have no fertility needs, are older or have serious conditions, especially those with complete hydatidiform mole or malignant transformation. Surgery can completely remove the lesion and reduce the risk of recurrence and malignant transformation. Regular follow-up is still required after surgery to monitor blood HCG levels and imaging examinations to detect abnormalities in a timely manner.

Patients with hydatidiform mole need to strictly observe contraception for 1 year after surgery to avoid another pregnancy interfering with follow-up results. Regularly check blood HCG and ultrasound examinations to monitor changes in the condition. Pay attention to supplementing protein, vitamins and minerals in the diet to promote physical recovery. Avoid excessive fatigue and mood swings, and maintain good living habits. If abnormal bleeding, abdominal pain or abnormally high HCG levels occur, seek medical attention in time. The treatment of hydatidiform mole needs to be individualized, and the appropriate plan should be selected based on the patient's age, fertility needs and severity of the disease. Postoperative follow-up and health management are equally important.