How to improve the treatment rate of advanced liver cancer? Several factors affecting the treatment of advanced liver cancer

Compared with other malignant tumors, liver cancer is one of the easiest cancers to diagnose. Early examination can detect liver cancer without symptoms. Once it is discovered when it is asymptomatic, the clinical treatment rate of liver cancer is as high as 60% to 70%. Therefore, early detection and early treatment are the prerequisites for the treatment rate of lung cancer. Among the more than 1,500 liver cancer patients who underwent surgery, less than 15% of them were discovered early. The vast majority of these patients survived for more than 5 years after surgery, and some have survived for more than 10 years. Another 75% of patients were already in the middle and late stages when they were examined, and any treatment was almost ineffective. Their 5-year survival rate was only less than 5%, and the treatment rate of liver cancer was very low.

Experts said that clinically, the five-year survival rate of liver cancer patients is generally used as the standard for clinical treatment of liver cancer. The five-year survival rate refers to the survival period of more than five years after surgical treatment, which is called the "five-year survival rate" or the commonly said clinical treatment rate. Therefore, it can be seen that clinical treatment is different from the disease recovery understood by ordinary people.

1. Factors related to the treatment rate of advanced liver cancer

The treatment of advanced liver cancer relies more on drug therapy, which mainly includes traditional Chinese medicine and chemotherapy. Chemotherapy has a more direct therapeutic effect on advanced liver cancer, which can shrink tumors and relieve symptoms to a certain extent. However, clinical statistics show that the effect of using chemical drugs alone for advanced liver cancer patients is not ideal. On the one hand, it is because the range of advanced liver cancer tumors is wide and there are many complications. On the other hand, it is because the physical function of patients with advanced liver cancer is already poor, and chemical drugs have greater toxic side effects, which will inhibit the body's immunity and cause damage to human functions. Although it can improve symptoms and prolong survival in the short term, the long-term effect is not good. Traditional Chinese medicine and Chinese medicine are used for systemic conservative treatment. The short-term effect is not as direct as chemotherapy, but it also has a significant effect in improving the quality of life and prolonging survival. Some data show that the treatment of advanced liver cancer with traditional Chinese medicine is better than that with chemotherapy. After one year of treatment with thiotepa and fluorouracil, the survival rates were 8.9% and 9.9%, respectively, while the one-year survival rate of the traditional Chinese medicine treatment group was 38.7%. Therefore, choosing the right treatment method is extremely important for how long patients with advanced liver cancer can live.

The patient's physical fitness is also an important factor in determining how long he can live in the late stage of liver cancer. Only with good physical function and strong immunity can he resist the development of cancer and tolerate various drug treatments. Therefore, it is extremely important for patients with advanced liver cancer to improve immune function and enhance resistance to tumors. First of all, in daily diet, you should eat small meals at regular times, quantitatively, and frequently to reduce the burden on the gastrointestinal tract; eat more foods containing vitamins, vegetables and fruits; often eat foods that have anti-cancer effects, such as kale and cabbage; insist on low-fat, high-protein, and easily digestible foods. In addition, you can also rely on taking Chinese medicine that has the effect of replenishing qi and nourishing the liver to enhance immune function.

2. Factors Affecting Liver Cancer Treatment

1. The prognosis of primary liver cancer mainly depends on the early or late stage of the disease

If a small primary liver cancer of 2 cm without organ invasion is removed, the 5-year survival rate can reach 60%-100%, while the 5-year survival rate after surgery for symptomatic patients is less than 20%. Therefore, the key is to detect primary liver cancer early.

Early surgical treatment is the fundamental method. At present, early hepatic lobectomy for small liver cancer can have the hope of radical cure. According to the location and size of the tumor, the choice of surgical method is also an important part to ensure the success of the operation. The general postoperative recurrence rate is 40%-60%, so chemotherapy is needed after surgery to achieve the purpose of treatment. Primary liver cancer is not easy to be found in the early stage, so 70% of patients have lost the opportunity for surgery when liver cancer is found. At present, the 5-year survival rate of non-surgical treatment is 20%. The choice of treatment plan has a great impact on prognosis. The efficacy of anticancer drugs alone is poor, and the use of combined or sequential treatment plans is expected to achieve better results. For patients who have lost the opportunity for surgery, hepatic artery chemoembolization should be performed. If combined with radiotherapy, the 3-year survival rate can reach 60%. -196℃ liquid nitrogen cryotherapy is simple and effective. It is applied to small liver cancer, and the 5-year survival rate can reach 50%. In addition, cyclosporine A is used after liver transplantation to inhibit immune rejection. In patients without lymphatic system metastasis, the 5-year survival rate can reach 60%, but only 15% with metastasis.

2. Relationship between treatment of primary liver cancer and immune function

Cellular immune functions such as T cells, lymphokine-activated cells (LAK), natural killer cells (NK), etc., their activity and the degree of lymphocyte infiltration around the tumor are the body's anti-tumor defense barrier. Normal immune function means a better prognosis. Patients with significantly elevated levels of transpeptidase (γ-GT) and alkaline phosphatase (ALp) produced by the deterioration and transformation of precancerous cells have a high recurrence rate after surgery. For patients with fetal thyroid gland (AFp) of 1000 micrograms/liter, the one-year survival rate is 100%; for patients with AFp <50001=““75=““afp=““">5000 micrograms/liter, the one-year survival rate is 51.3%.

3. How to improve the treatment rate of advanced liver cancer

The treatment of advanced liver cancer relies more on drug therapy, which mainly includes traditional Chinese medicine and chemotherapy. Chemotherapy has a direct effect on advanced liver cancer, and can shrink tumors and alleviate symptoms to a certain extent. However, clinical statistics show that the effect of using chemical drugs alone on patients with advanced liver cancer is not ideal. On the one hand, it is because the tumor range of advanced liver cancer is wide and there are many complications. On the other hand, it is because the physical function of patients with advanced liver cancer is already poor, and chemical drugs have greater toxic side effects, which will suppress the body's immunity and cause damage to human functions. Although it can improve symptoms and prolong survival in the short term, the long-term effect is not good. However, the conservative treatment of systemic traditional Chinese medicine is effective.

1. Minimize complications. Hypersplenism is the most serious complication of most liver cancer patients. It can cause abnormal hematopoietic mechanism and coagulation dysfunction. Combined with portal hypertension, it causes highly varicose veins at the fundus of the stomach, which can easily cause massive gastrointestinal bleeding. Abnormal liver function can also lead to insufficient protein synthesis, low protein, and a large amount of ascites. Tumor compression can also cause bile excretion disorders, causing jaundice, etc. Treatment using the characteristics of traditional Chinese medicine such as strengthening the spleen and regulating qi, promoting digestion, softening and dispersing nodules can achieve the effect of reducing AFp, normalizing liver function, increasing phagocytes, T cells, and tumor necrosis factor, promoting the increase of patients' food intake, eliminating ascites, removing jaundice, and controlling the continued growth of tumors.

2. Protect liver function to the maximum extent. The liver is the largest digestive gland in the human body. Its task is quite arduous. It is involved in various digestive metabolism, absorption and utilization activities of the body. Once liver function is abnormal, a series of disorders such as sugar metabolism, protein metabolism, and fat metabolism will occur. Most liver cancer patients die of liver failure or massive gastrointestinal bleeding caused by portal hypertension due to abnormal liver function. Traditional Chinese medicine treatment is to restore and protect the liver to the maximum extent based on syndrome differentiation. The focus is not on the tumor but on the improvement of symptoms. When the symptoms improve, the tumor will naturally stabilize or shrink.

3. Improve the quality of life and living of patients to the greatest extent. Cancer is still a stubborn disease in the world. No doctor in a regular hospital dares to claim to have cured the disease. However, in view of the characteristics of liver cancer, such as rich blood supply, double blood supply, rapid metastasis and rapid growth, TCM focuses on peripheral symptoms and adopts the strategic idea of ​​"surrounding the city from the countryside", which relieves many symptoms caused by the primary lesion. Patients treated by TCM generally do not feel pain, ascites disappears, liver function drops to normal, jaundice subsides, and the goal of "surviving with tumor" is achieved. Patients who originally lived for 3 to 6 months can extend their survival to 1 to 3 years, or even longer, and they can take care of themselves and participate in some sports activities.

In general, the survival period of advanced liver cancer varies from person to person. The patient's physical fitness, psychological quality, and whether the treatment method is appropriate will affect the length of survival. In addition, whether the treatment method is appropriate is also a key factor that directly affects the survival period of advanced liver cancer. It is most important to receive regular treatment as soon as possible.