What is the chance of inheriting liver cancer? You need to know these common liver cancer facts

Nowadays, people are prone to various diseases due to unhealthy diet, smoking, drinking, etc., as well as unstable work and rest schedules. What is particularly worrying is what to do if the malignancy turns into cancer. Liver cancer, which is common among cancers, must be paid attention to. For the sake of health, please go to the hospital for regular physical examinations. So what is the probability of liver cancer inheritance?

Is liver cancer inherited genetically? What is the probability of genetic inheritance?

As to whether liver cancer is a hereditary disease, experts from all over the world have basically reached a consensus: liver cancer is a multi-genetic disease, and its occurrence is the result of the combined effects of genetic and environmental factors.

In other words, genetic factors are the basis, which determine the body's susceptibility to tumors; environmental and other risk factors such as hepatitis B virus infection (hepatitis B and C), intake of aflatoxin in food, long-term excessive drinking and excessive fatigue, etc., contribute to the occurrence of liver cancer.

Studies have found that genetic polymorphisms of some genes related to immunity, inflammation, DNA repair, cell proliferation, apoptosis and its carcinogenic compounds, and alcohol metabolism and detoxification are closely related to liver cancer susceptibility genes.

For example, the liver is the body's main detoxifying organ. Some people have a strong ability to detoxify carcinogens, so the amount accumulated in the body is small, while some people have a poor detoxifying ability, so the amount accumulated is large.

Description of the Clinical Epidemiology Survey on Hepatocellular Carcinoma Genes:

In a family with a high incidence of liver cancer, the incidence of liver cancer in cohabiting families is higher than that in non-cohabiting families; the cancer rate of offspring whose fathers have liver cancer is 29.3%; and the cancer rate of offspring whose mothers have liver cancer is 41.7%; among first-degree relatives, siblings have the highest risk of cancer. The above data show the existence of environmental risk factors in the development of liver cancer, and their role cannot be ignored. Compared with the proportion of genetic factors, external factors account for about 90% of liver cancer.