Cervical atypical hyperplasia and cervical carcinoma in situ have the same epithelial changes, but the degree is different. Cervical atypical hyperplasia is milder. According to the degree of cell atypia, CIN is divided into three levels: I mild cervical atypical hyperplasia, moderate cervical atypical hyperplasia, and cervical carcinoma in situ. CIN of various grades has a tendency to develop into invasive cancer. Generally speaking, the higher the grade, the greater the chance of developing into invasive cancer; the lower the grade, the greater the chance of natural regression. Cervical dysplasia refers to partial or major abnormalities and atypical differentiation of cervical epithelial cells. Cervical dysplasia can occur at the external cervical os, transitional zone, or endocervical surface. Cervical carcinoma in situ refers to atypical hyperplasia of the cervix involving the squamous epithelium, but does not break through the basement membrane or invade the stroma, and the lesions are confined to the squamous epithelium. Patients with CIN generally have no obvious symptoms, or only have general cervicitis symptoms, such as increased leucorrhea. They also complain of leucorrhea or a small amount of vaginal bleeding after sexual contact. Gynecological examination shows that the cervix is smooth without obvious inflammation, or the cervix is congested or eroded with varying degrees and ranges of erosion, and sometimes it is easy to bleed, which is no different from general chronic cervicitis. Cervical dysplasia is a precancerous lesion that is reversible, meaning some lesions can disappear naturally, but it is also progressive, meaning the lesions can develop and even become cancer. Its reversibility and progression are related to the extent and degree of the lesion. The possibility of mild atypical hyperplasia disappearing naturally is significantly greater than that of moderate and severe hyperplasia. The possibility of severe atypical hyperplasia developing into cancer is significantly greater than that of mild and moderate hyperplasia. Some scholars also believe that mild atypical cervical hyperplasia is a benign proliferation that can naturally transform into normal. |
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