What is the safe value of TSH after thyroid cancer surgery? What is the standard of safe value of TSH after thyroid cancer surgery?

Thyroid cancer surgery can effectively protect the health of thyroid cancer patients, prevent the disease from worsening, and effectively organize the metastasis and spread of cancer cells. In my country's medical clinical practice, more and more patients are undergoing this surgery. The safety factor of this surgery is relatively high. After thyroid cancer surgery, patients need to carefully observe the TSH safety value for a long time.

The low-risk group for recurrence must meet all of the following conditions: no local or distant metastasis; all macroscopically visible tumors have been removed; the tumor has not invaded surrounding tissues; the tumor is not an invasive histological subtype and there is no vascular invasion; whole-body iodine-131 imaging after thyroidectomy shows no iodine uptake outside the thyroid bed.

The intermediate-risk group for recurrence must meet one of the following conditions: pathological examination after the initial surgery can reveal soft tissue invasion around the thyroid gland under the microscope; there is cervical lymph node metastasis; the tumor is an invasive histological subtype; the tumor invades the blood vessels; whole-body iodine-131 imaging after thyroidectomy shows iodine uptake outside the thyroid bed.

The high-risk group must meet one of the following conditions: the tumor can be seen invading surrounding tissues or organs under the naked eye; the tumor cannot be completely removed and there is tumor residue during surgery; there is distant metastasis; the serum thyroglobulin (Tg) level is still high after total thyroidectomy; there is a family history of thyroid cancer.

In the first year after surgery, patients with high- to medium-risk recurrence should have a TSH <0.1mU/L after surgery. For patients with low risk of recurrence, it depends on the risk of the drug. For patients with small drug side effects, the low-risk drug group is 0.1-0.5mU/L, and for patients with large side effects, the TSH is 0.5-1mU/L. One year after surgery, we will evaluate the patient again: patients with high- to medium-risk recurrence and low drug risk have a TSH <0.1mU/L, but if the patient has adverse reactions to thyroid hormone treatment, the TSH control target can be adjusted to 0.1-0.5mU/L. For patients with low risk of recurrence and small adverse drug reactions, it is recommended that TSH be controlled at 0.5-2.0mU/L. However, if the patient has adverse reactions to treatment, the TSH control target can be adjusted to 1-2mU/L.