What to do if liver disease virus index is high

Virus-induced liver disease is very serious because many patients often have various problems after developing liver disease. In order to ensure their health, people should usually do some physical examinations. After using the instrument to check, if the liver virus is found to be serious, timely treatment should be required. If delayed, it may be life-threatening, so what should we do if the liver disease virus index is high?

The five items of hepatitis B are also called hepatitis B two pairs and a half, including hepatitis B surface antigen (HBSAg), hepatitis B surface antibody (HBSAb/anti-HBs), e antigen (HBeAg), e antibody (HBeAb/anti-HBe), and core antibody (HBcAb/anti-HBc). The five-item hepatitis B test involves drawing venous blood from the patient and testing the serological markers of hepatitis B virus in the blood.

Reference range of five hepatitis B tests:

Hepatitis B surface antigen (HBsAg) -0--0.5ng/mL HBsAg greater than 0.5ng/mL +

Hepatitis B surface antibody (HBsAb) - 0--10mIU/mL HBsAb is greater than 10mIU/mL + (no infection with antibodies, 0~10mIU/mL weak positive)

Hepatitis B e antigen (HBeAg) -0--0.5PEI/mL HBeAg greater than 0.5PEI/mL + (less than 0.5PEI/mL negative —- )

Hepatitis B e antibody (HBeAb) - 0--1.5PEI/mL Hepatitis B e antibody greater than 1.5P /mL +

Hepatitis B core antibody (HBcAb) -0--0.9PEI/mL HBcAb greater than 0.9PEI/mL +

Indicator Details

1. HBsAg (Hepatitis B surface antigen) It is the outer shell material of the hepatitis B virus and is not contagious in itself. Its positivity often indicates the presence of complete virus particles.

2. Anti-HBs (Hepatitis B surface antibody, HBsAb) is an antibody that appears during the recovery period of people naturally infected with HBV, at which time HBsAg disappears naturally. Its existence indicates that people have become resistant to hepatitis B and will not get hepatitis B again. 27.42% of the population in our country has this antibody.

3. HBeAg (hepatitis B e antigen) It is produced inside the virus and can be secreted into the blood. A positive e antigen indicates that the virus is active. The hepatitis B virus replicates very quickly and is an indicator of infectiousness.

4. Anti-HBe (Hepatitis B e antibody, HBeAb) is a protein substance produced by the human body against the e antigen. A positive result indicates that the virus's infectiousness has weakened and the disease is in the recovery stage. But another possibility is that the hepatitis B virus has mutated. At this time, there is no HBeAg in the serum, but anti-HBe can be produced. In this case, HBV-DNA needs to be checked to determine whether the virus still exists.

5. Anti-HBc (hepatitis B core antibody, HbcAb) This antibody is divided into two types: IgM and IgG. A positive anti-HBc-IgM indicates viral activity and is contagious; a positive anti-HBc-IgG indicates a previous infection, which is not contagious and does not require antiviral treatment.

In addition, HBV-DNA is the genetic gene of the virus and exists in the core part of the virus. Its positive meaning is basically the same as that of HBeAg positive. Therefore, it is generally recognized that the effectiveness of antiviral treatment is mainly based on the negative conversion or significant quantitative reduction of HBeAg and HBV-DNA.