What are the symptoms of hamartoma

The incidence of hamartoma has been on the rise in recent years. Since this tumor originates from different tissues, it is still relatively common in clinical practice. The symptoms of hamartoma cannot be generalized. The symptoms of tumors in different parts of the body are different. Later, I will introduce to you the symptoms of hamartoma by category.

Hamartoma is not a true tumor. It grows slowly and increases with the development and growth of the body, but it stops growing to a certain extent. It is coordinated with the body and rarely becomes malignant. Some scholars also believe that hamartoma is a true tumor (such as renal angiomyolipoma) rather than an "abnormal combination of normal tissues" and should be classified as a mesenchymal tumor.

Pulmonary hamartoma: a piece of bronchial tissue inverts and falls off during embryonic development and is surrounded by normal lung tissue. This part of tissue grows slowly or may not grow for a certain period of time, and then gradually develops into a tumor. Most cases occur after the age of 40.

Renal Hamartoma: Renal Hamartoma, also known as renal angiomyolipoma, is a benign tumor. Over the years, the incidence has tended to increase, which may be related to the improvement of diagnostic technology. Renal Hamartoma can be an independent disease or accompanied by tuberous sclerosis, the latter of which is autosomal dominant. The clinical features are multiple lesions in both kidneys, combined with mental retardation, butterfly-shaped sebaceous adenoma on the face, etc. It is more common in women, and the age of onset is mostly 20-50 years old. However, the vast majority of patients with renal Hamartoma in my country do not have tuberous sclerosis.

Biliary hamartomas: Biliary hamartomas (also called von Meyenburg complexes) are hamartomatous lesions caused by impaired transformation of the bile duct plate into the bile duct during embryonic development and insufficient absorption. The disease is also called von Meyenburg syndrome, which is characterized by multiple, uniformly sized cystic lesions surrounded by varying amounts of fibrous matrix. The incidence of biliary hamartomas is about 1% to 3%. Generally, there are no clinical symptoms and they are discovered accidentally, and no special treatment is required. There have been reports of successful liver transplantation using livers with biliary hamartomas as donor livers. There are literature reports that the disease can cause unclear abdominal pain and malignant transformation.

Differential diagnosis : includes liver metastasis and small liver abscess. If abdominal MRI confirms that the lesion is cystic, uniform in size, equal in signal intensity, and has clear boundaries, the above lesions can be excluded.