What are the early symptoms of hamartoma

Nowadays, with the improvement of material life, people's awareness of physical examination is also increasing. Regular physical examination is a very beneficial thing. It can not only detect diseases as early as possible and treat them as early as possible, but also help people get rid of their unnecessary worries and suspicions and enhance their confidence in a positive life. Today, I will explain to you what are the early symptoms of hamartoma.

Hamartoma: refers to a tumor-like deformity caused by the incorrect combination and arrangement of normal tissues in an organ of the body during development.

Hamartomas can arise from many tissues, most commonly in the lung (localized or diffuse hamartomas formed by a mixture of cartilage islands, bronchial epithelium, and glandular tissues, and localized proliferation), kidney (angiomyolipomas), breast (mammary hamartomas formed by mammary lobular fat), and infant liver (mesenchymal hamartomas).

Most patients with hamartomas have no symptoms. The main reasons for the symptoms are mostly related to the location, size, number, growth rate, and relationship between the hamartoma and surrounding organs. During the physical examination, it is often found that some patients may have the following symptoms due to the tumor itself, increased pressure in the tumor, infection, etc.:

① Discomfort or pain in the waist and abdomen: The reason is that the enlarged and expanded kidneys increase the tension of the renal capsule, pull the renal pedicle, or compress adjacent organs. In addition, the large size of the renal hamartoma causes the kidneys to become heavy, which can also cause lumbar pain. The pain is characterized by dull pain, fixed on one side or both sides, radiating to the lower body and lower back. If there is bleeding in the tumor or secondary infection, the pain will suddenly intensify. If combined with stones or blood clots after bleeding that block the urinary tract, renal colic may occur.

②Hematuria: It can be manifested as microscopic hematuria or macroscopic hematuria. The attack is cyclical. The back pain often intensifies during the attack. Vigorous exercise, trauma, and infection can induce or aggravate it.

③Abdominal mass: Sometimes it is the main reason for patients to seek medical treatment. 60% to 80% of patients can feel enlarged kidneys.

④ Proteinuria: Generally, the amount is not much, and will not exceed 2g in 24 hours. Nephrotic syndrome will not occur.

⑤ Hypertension: The tumor compresses the kidneys, causing renal ischemia, increasing renin secretion, and causing hypertension. When renal function is normal, more than 50% of patients have hypertension, and the incidence of hypertension is even higher when renal function is impaired.

⑥ Decreased renal function: Due to the tumor's space occupation and compression, the normal renal tissue is significantly reduced and renal function progressively declines.

It can be seen that the early symptoms of hamartoma are not obvious, so it is very important to have regular physical examinations. I wish you good health!