How do you get a pituitary tumor?

Because pituitary tumors occur in the brain, their onset brings great pain to many patients, and in severe cases they are even life-threatening. Many patients do not know why they suffer from pituitary tumors. In fact, its causative factors are very complex. So, how do pituitary tumors occur? Let us take a look at the causes of its disease.

Causes of pituitary tumors:

1. Genetics such as multiple endocrine neoplasia 1 (MEN1), excessive PROP-1, and transcription factor defects;

2. Hypothalamic lesions such as excess GHRH or CRH, dopamine deficiency, and possible receptor activation;

3. Somatic signal transduction mutations such as abnormal growth factor and cytokine action;

4. Gene activation or disruption of cell cycle regulation;

5. Oncogene loss, oncogene GSP, RAS mutation, PTTG-1; radiation effects, estrogen application;

6. Environmental factors;

7. Damage to surrounding structures of the tumor: As the tumor grows, it invades and compresses surrounding important structures, such as the optic nerve, cavernous sinus, basilar cerebral artery, hypothalamus, third ventricle, brain stem, etc., leading to corresponding functional disorders, manifested as decreased vision, visual field defects, hemiplegia, fixed eyeballs, diplopia, intellectual and memory disorders, mental changes, headaches, hydrocephalus, etc.

8. Endocrine disorders: Pituitary tumors with secretory functions secrete hyperhormones, causing an increase in the patient's PRL, GH, ACTH, TSH and other hormones, thereby causing menstrual disorders, lactation, miscarriage, infertility, sexual dysfunction, obesity, ugly face, gigantism, enlarged hands and feet, increased hair, rough skin, etc.; those with hypopituitarism will show symptoms of fatigue, fear of cold, etc.

9. Metabolic disorders: decreased blood potassium, sodium, chloride, and calcium, weakness, vomiting, nausea, diarrhea, abdominal distension, spontaneous fractures in multiple parts of the body (most common in ribs and vertebrae). Low immune function: easy to catch a cold and cancer. Psychological pressure. Pituitary tumors can occur at any age, but they are more common in young and middle-aged people. Because pituitary tumors have serious damage to human growth, development, physical and mental health, fertility, and multi-organ functions, patients with pituitary tumors should actively seek early treatment.

Due to the repeated effects of various factors, the impact of pituitary tumors on the body is immeasurable. In order to avoid the invasion of the disease and maintain a harmonious and happy family life, we must make more efforts, start from the details of our lives, and then effectively prevent the occurrence of pituitary tumors. This is very important.