Experts explain the symptoms of bone metastasis of malignant melanoma

Malignant melanoma is not a very common disease in China, but the mortality rate is very high. Once bone metastasis occurs, it is even more serious. What are the main symptoms of malignant melanoma bone metastasis? Let's ask the experts to tell us in detail about the symptoms of malignant melanoma bone metastasis .

The prognosis of malignant melanoma bone metastasis is often poor, with a life expectancy of 3.6.5.6.7 months. Melanoma metastases from the primary site to bone tissue through lymphatic and blood routes. Most bone metastases occur in the vertebrae, mainly in the thoracic vertebrae. There are also reports of spinal cord metastasis. Spinal metastatic melanoma without a clear primary focus is rare. The incidence rate is reported in the literature to be 0.37%.

The first symptom of malignant melanoma bone metastasis without a clear primary focus is back pain. The pain is mostly caused by tumor invasion of the vertebral body, resulting in microfractures or stimulation and compression of nerve tissue. When the lesion destroys the pedicle, neurological symptoms may occur. Many benign lesions often present with back pain as the first manifestation, so clinical differentiation should be made between cancerous back pain and benign back pain, so as to detect spinal metastatic tumor lesions as early as possible.

Spinal MRI is the first choice to determine whether there is destruction or space-occupying lesions of the spine. It can also evaluate the invasion of soft tissue and spinal nerves. High-resolution MRI is an effective method for detecting tiny melanoma lesions, which can detect tiny metastatic lesions of 0.323 mm2. Bone scans are highly sensitive to bone metastases of melanoma and can detect early tiny metastatic lesions. The diagnosis of bone melanoma depends on comprehensive clinical, imaging, and pathological manifestations.

The above is the introduction of "Symptoms of Bone Metastasis of Malignant Melanoma", for participation only. There are many symptoms of bone metastasis of malignant melanoma, which we should pay attention to and prolong the patient's life. If you have other questions about the symptoms of bone metastasis of malignant melanoma, please consult our online experts for more information.

For more information, please visit the melanoma special topic at http://www..com.cn/waike/hssl/ or consult an expert for free. The expert will then give a detailed answer based on the patient's specific situation.