Basic examination of osteosarcoma

Osteosarcoma is a malignant tumor with a high mortality rate among children and adolescents, but early detection and timely treatment have greatly improved the survival rate of the disease, so examination is very important. The earlier the examination is done, the earlier the diagnosis is confirmed, and the earlier the treatment is. Do you know what are the basic examinations for osteosarcoma?

Examination of osteosarcoma: In cases of osteogenic osteosarcoma, elevated levels of bone-derived alkaline phosphatase in the blood can be found in the early stages, which is related to the osteogenesis of the tumor. Pathological diagnosis is the basis for treatment. When considering the diagnosis of osteosarcoma, a biopsy is performed to confirm the pathological examination as soon as possible, which is of great significance for the diagnosis and treatment.

1. X-ray

The X-ray manifestation of a typical osteosarcoma is that the bone tissue has the characteristics of new bone formation and bone destruction at the same time. The tumor is mostly located at the metaphysis of the long tubular bone, with unclear edges, destroyed trabeculae, and increased tumor tissue density. After penetrating the bone cortex, the tumor lifts the periosteum, producing the characteristic X-ray sign of the disease - Codman's cuff triangle (Codman-triangle). This phenomenon can be seen in some patients with osteomyelitis and Ewing's sarcoma, and is very typical in osteosarcoma. In the late stage, the shadow of the tumor infiltrating the soft tissue can be seen, and pathological fractures can be seen in some cases.

2. CT scan and MRI

It is an effective means to determine the nature and extent of bone tumors and the presence or absence of surrounding soft tissue infiltration. It can detect metastatic lesions to the lungs and other organs at an early stage and is a routine item in the clinical examination of osteosarcoma.

3. Nuclear bone scan

It is a commonly used method for early detection and late identification of the presence or absence of metastatic lesions.

Osteosarcoma diagnosis: The diagnosis can be made based on medical history, clinical manifestations and auxiliary examinations. Osteosarcoma should be differentiated from osteomyelitis and Ewing sarcoma.