Introduction to the diagnosis methods of osteosarcoma

Before osteosarcoma appears, pain is an early symptom. It is intermittent pain at first, and gradually turns into continuous severe pain, especially at night. Does similar pain mean osteosarcoma? Of course not. How to diagnose osteosarcoma? The following introduces the common diagnostic methods of osteosarcoma.

1. It is common in adolescents aged 15-25 years old, and is more likely to occur in the epiphyses of the long bones of the limbs. It is most common above and below the knee joint.

2. The main symptom is local pain, which is intermittent dull pain at first and quickly turns into continuous severe pain, especially at night.

3. The local skin temperature is high, the veins are dilated, the mass grows rapidly, there is tenderness, tremors and vascular murmurs may occur, and there may be pathological fractures and joint dysfunction.

4. Systemic toxic reactions, loss of appetite, weight loss, and finally exhaustion and cachexia.

5. Anemia, increased white blood cell count, blood sedimentation rate, increased alkaline phosphatase

6. Characteristics of X-ray films.

7. Pathological examination can confirm the diagnosis.

Differential Diagnosis

1. It needs to be differentiated from chronic suppurative osteomyelitis, Ewing's sarcoma, and metastatic bone tumors.

2. Chronic suppurative osteomyelitis: The density of the medullary cavity is diffusely increased, the cortex is thickened, but there is no large-scale bone destruction or tumor bone formation, and soft tissue swelling is not obvious. If dead bone is seen, the diagnosis of osteomyelitis is more clear.

3. Ewing's sarcoma presents as spotted and rat-bite-like osteolytic destruction in the medullary cavity, covering a relatively long area, and often with onion-skin-like periosteal reaction.

4. Metastatic tumors rarely invade the bones near the knee joint, and are more likely to occur in the pelvis and spine. The bone changes are mostly osteolytic, and most of them have no periosteal reaction and soft tissue masses.