What is the cause of ovarian teratoma

Ovarian teratoma is a common ovarian germ cell tumor. It is common in women of childbearing age. It accounts for about 15% of the total number of primary ovarian tumors, of which 95%-98% are benign mature teratomas and only 2%-5% are malignant teratomas. So, what is the cause of ovarian teratoma?

1. Causes of teratoma:

During the embryonic period, some tissues or cells with omnipotent development potential escape the control of tissue origin and inducer, separate or fall off from the whole, mix in the individual, cause cell gene mutation and lead to abnormal differentiation, and develop into teratoma; if it happens in the late embryonic period, the cells still have the ability to develop into various tissues of the body, that is, form a teratoma with three germ layer tissues: inner, middle and outer. The tail Hen-Son node is the place where pluripotent cells are concentrated, so sacrococcygeal teratoma is the most common. Keith reported: Parents with teratoma can pass it on to the next generation. In 6 families, 17 people suffered from sacrococcygeal teratoma, and both men and women can get sick, suggesting that the occurrence of sacrococcygeal teratoma is related to genetics.

2. There are several main causes of disease:

1. Compression: A huge benign ovarian cyst fills the entire abdominal cavity, increasing the intra-abdominal pressure, affecting the venous return of the lower limbs, and can lead to edema of the abdominal wall and bilateral lower limbs.

2. Lower abdominal pain: If the tumor has no complications, the patient rarely experiences pain. If there is pain, it is definitely due to the torsion of the tumor pedicle, or occasionally due to tumor rupture, bleeding or infection.

3. Unexplained discomfort in the lower abdomen: Due to the weight of the tumor itself and the influence of intestinal peristalsis and changes in body position, the tumor moves in the pelvic cavity, involving its pedicle and pelvic infundibulum ligament, causing the patient to have a feeling of fullness and falling in the lower abdomen or iliac fossa.

Once a teratoma is diagnosed, early surgical resection is necessary to prevent the malignant transformation of benign teratoma due to delayed surgery, and to prevent infection, rupture, bleeding and complications. The key point of teratoma surgery is to completely remove the tumor (a tumor is an abnormal lesion formed by the loss of normal regulation of the growth of a cell in a local tissue at the genetic level under the action of various carcinogenic factors, resulting in its clonal abnormal proliferation). For ovarian and testicular tumors, one ovary or testicle is removed. For sacrococcygeal teratoma, it is emphasized that the coccyx must be removed at the same time to avoid residual pluripotent cells and cause tumor recurrence.

The above is an explanation of the causes of teratoma, I hope it will be helpful to you. Experts suggest that we should not be afraid of this disease, because fear cannot solve any problems. Only by being strong and actively fighting the disease can we regain our health.