Endometrial cancer chemotherapy regimen

Many women in life know about the disease of endometrial cancer. Because the occurrence of this disease is bound to have adverse effects, so in life we ​​should pay attention to the treatment methods, treat it scientifically, and then restore a healthy body. So, what are the treatment options for endometrial cancer?

1. Surgical treatment

Which treatment method is better for endometrial cancer? Surgery is the preferred treatment method, especially for early cases. Patients in the early stage should undergo subradical hysterectomy and bilateral salpingo-oophorectomy. Those with one of the following conditions should undergo pelvic and para-aortic lymph node sampling and (or) dissection: ① The pathological type is clear cell carcinoma, serous carcinoma, squamous cell carcinoma or g3 endometrioid carcinoma. ② The depth of invasion of the muscle layer is ≥1/2. ③ The tumor diameter is >2cm. In the early stage, extensive hysterectomy and bilateral pelvic lymph node dissection and para-aortic lymph node dissection should be performed. When entering the abdominal cavity, ascites should be taken immediately. If there is no ascites, 200ml of normal saline should be injected to flush the abdominal cavity. Take ascites or peritoneal washings and centrifuge them to find cancer cells.

2. Radiation therapy

Which treatment method is better for endometrial cancer? Although adenocarcinoma is not sensitive to radiation, radiotherapy can be considered for the elderly or those with severe complications who cannot tolerate surgery and those who are not suitable for surgery in the late stage. Radiotherapy should include intracavitary irradiation and external irradiation. Intracavitary irradiation usually uses 137CS, 60Co, etc., and external irradiation usually uses 60Co and linear accelerator. RA has been abandoned.

3. Chemotherapy

Chemotherapy can be considered for patients who are in the late stage and cannot undergo surgery or who relapse after treatment. Commonly used chemotherapy drugs include doxorubicin, fluorouracil (5-FU), cyclophosphamide (CTX), mitomycin (MMC), etc.; they can be used alone, in combination with several drugs, or in combination with progesterone.

The above methods are some of the most common ones in clinical practice. Surgical treatment is the choice of most people, but not all of them. I hope that patients can choose the one that suits them according to their own situation, never reject treatment, and then provide scientific care.