The most important diagnostic basis for endometrial cancer

What are the diagnoses for endometrial cancer? The diagnosis of endometrial cancer is generally not difficult, but sometimes it can be confused with other diseases, which can delay the diagnosis of endometrial cancer and make the treatment of endometrial cancer unreliable. The following is a detailed introduction to the diagnoses for endometrial cancer, hoping to help everyone.

What is the diagnosis of endometrial cancer?

Diagnosis of endometrial cancer: atypical endometrial hyperplasia

Atypical endometrial hyperplasia is common in women of childbearing age. Severe atypical endometrial hyperplasia is sometimes difficult to distinguish from well-differentiated adenocarcinoma in terms of tissue morphology.

Differentiate from well-differentiated early endometrial adenocarcinoma:

① Atypical hyperplasia often has complete surface epithelium, while adenocarcinoma does not. Therefore, if a relatively complete or flattened surface epithelium is seen, endometrial adenocarcinoma can be ruled out. In addition, endometrial adenocarcinoma often has necrosis and bleeding;

② Different responses to drug treatment. For patients with atypical hyperplasia, a smaller dose means a slower effect and a longer duration. Once the drug is stopped, the disease may relapse quickly.

③Age: Young people are more likely to consider atypical hyperplasia, while those with challenging personality are more likely to consider the possibility of endometrial adenocarcinoma.

Diagnosis of endometrial cancer II: postmenopausal bleeding

First of all, we should be alert to whether it is a malignant tumor, although the proportion of malignant tumors in postmenopausal bleeding has greatly decreased with the progress of the years. In terms of the age of menopause, 14% of women have been menopausal for 5 years, and 68.3% of women have been menopausal for 5 to 15 years. It can be seen that among malignant tumors, endometrial cancer has an upward trend with the progress of the years. The amount of bleeding may be small, the number of bleeding times is not large, and the cancerous lesions may be more obvious. Therefore, a careful gynecological examination should be performed to find out whether there are any abnormalities in the vagina, cervix, uterine body, and appendages. Since there may be more than two lesions at the same time, such as senile vaginitis and endometrial cancer at the same time, further examination should never be ignored because one lesion has been found.

Diagnosis of endometrial cancer III: dysfunctional uterine bleeding

Menstrual disorders often occur during menopause, especially those with frequent uterine bleeding. Regardless of whether the size of the uterus is normal, a diagnostic curettage must be performed first to determine the nature of the problem before treatment.

Diagnosis of endometrial cancer IV: senile vaginitis

The main manifestation is bloody leucorrhea, which needs to be differentiated from endometrial cancer. The former shows congestion of the vaginal wall or scattered bleeding spots under the mucosa, while the latter shows normal vaginal wall and the discharge comes from the cervical canal. Elderly women should also pay attention to the possibility of the two conditions coexisting.

Endometrial cancer diagnosis 5: cervical cancer

Like endometrial cancer, it also presents with irregular vaginal bleeding and increased discharge. If the pathological examination shows squamous cell carcinoma, it is considered to originate from the cervix. If it is adenocarcinoma, it will be difficult to identify its source. If mucous glands can be found, it is more likely to originate from the endocervical canal.

Diagnosis of endometrial cancer 6: Uterine submucous osteoma or endometrial polyp

The symptoms are often menorrhagia or prolonged menstruation, or bleeding accompanied by vaginal discharge or bloody secretions. The clinical manifestations are very similar to endometrial cancer. However, differential diagnosis can be made through uterine cavity exploration, segmental curettage, hysteriodized oil contrast, or hysteroscopy.

Diagnosis of endometrial cancer VII: Primary fallopian tube cancer

Vaginal discharge, vaginal bleeding and lower abdominal pain, vaginal smear may find cancer cells and are similar to endometrial cancer. However, endometrial biopsy of fallopian tube cancer is negative, and a mass can be felt around the uterus, which is different from endometrial cancer. If the mass is small and not palpable, it can be confirmed by laparoscopy.

Diagnosis of endometrial cancer VIII: Senile endometritis combined with intrauterine pyometra

It is often manifested as vaginal discharge of pus, blood or purulent blood, and the uterus is often enlarged and softened. After B examination and expansion of uterine cancer tissue, only inflammatory infiltrated tissue is seen. Pyometra often coexists with cervical canal cancer or endometrial cancer, and care must be taken when distinguishing.

The above is a detailed explanation of the diagnosis of endometrial cancer. Being familiar with the differential diagnosis of endometrial cancer will help to accurately diagnose and treat endometrial cancer, thereby improving the treatment effect of endometrial cancer. If you find the above symptoms, you need to go to a regular hospital for treatment in time. I wish you all good health!