What is the cause of gallbladder cancer in the elderly?

What is the cause of gallbladder cancer in the elderly?

Gallbladder cancer has a particularly high mortality rate. After contracting this disease, patients are often prone to metastasis of cancer cells if they are not careful during treatment. The consequences are often very terrible, so we must prevent the metastasis of cancer cells and avoid some unfavorable factors. The article below is about what factors can cause the metastasis of gallbladder cancer.

1. Tumor local factors: including tumor size, growth rate, degree of differentiation, pathological type, tumor cell metabolic characteristics, motility, annual benefits, enzyme production, surface structure and charge, tumor angiogenesis, changes in cancer cell DNA structure, etc. Generally speaking, the larger the tumor, the higher the malignancy, the faster the growth rate, and the easier it is to metastasize.
2. Systemic factors: In addition to local factors, malignant tumors are also affected by many systemic factors, mainly:
① Immune function: The body's immune function plays an important role in the occurrence of tumors. Similarly, in the process of tumor metastasis, the normality of the immune status plays a leading role in the early or late occurrence of metastasis and the speed of metastatic tumor growth. People with good immune status can inhibit tumor metastasis, making the tumor stable for a long time and in a self-limiting state. If the body's immune system's ability to resist tumors is reduced, early metastasis may occur.
② Coagulation mechanism: Tumor metastasis must go through a series of processes such as tumor cell adhesion to vascular endothelial cells, fibrin wrapping, and tumor thrombus formation. In this process, the role of coagulation and anticoagulation mechanisms in metastasis has attracted widespread attention. Studies have found that cancer cells themselves can produce procoagulant factors that facilitate vascular epithelial adhesion and promote metastasis.

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