What causes pancreatic cancer

In daily life, we should learn about pancreatic cancer as early as possible, because this disease will cause the patient's pancreatic function to decline, seriously affecting the patient's body. Therefore, we need to pay attention to the occurrence of the disease and understand the development factors of the disease as early as possible. The following introduces the causes of pancreatic cancer.

Drinking: Drinking is closely related to the occurrence of many tumors, and the incidence of pancreatic cancer varies among different races. According to a study by Silverman et al. on the relationship between drinking and the incidence of pancreatic cancer in black and white Americans, black male heavy drinkers and female moderate drinkers have a higher incidence rate than whites.

Diabetes: Experimental studies have shown that insulin can promote the growth of pancreatic cancer cells in vitro or in vivo; high concentrations of insulin can activate the insulin-like growth factor-1 receptor, producing a growth-promoting effect including changes in cell cycle progression.

Helicobacter pylori: (HP) studies have shown that HP serum is positive in pancreatic cancer patients, which is significantly different from the control group, suggesting that HP infection is related to pancreatic cancer.

Chronic pancreatitis: Most epidemiological and molecular epidemiological studies support that chronic pancreatitis can develop into pancreatic cancer. Friess's study showed that among 5,600 genes, 34 genes were expressed less in patients with pancreatic cancer and chronic pancreatitis, 157 genes were expressed more strongly in chronic pancreatitis, and 152 of them were also expressed more strongly in pancreatic cancer. This study proved at the molecular level that there may be some connection between chronic pancreatitis and pancreatic cancer.

Coffee: Surveys have found that coffee can increase the risk of pancreatic cancer by four times. Studies have shown that coffee can inhibit DNA repair and induce mitosis before DNA replication is completed, which is the main cause of cancer.

In normal times, we need to pay attention to the causes of this disease, we must pay attention to the occurrence of chronic pancreatitis, and pay attention to early treatment, so as to get rid of the impact of the disease. In normal times, we need to pay attention to care methods, and pay attention to a scientific and balanced diet, and in daily life, we must also pay attention to reasonable diagnosis and do not smoke and drink a lot.