Uterine cancer is one of the most common malignant tumors in gynecology. Uterine cancer includes uterine body cancer (also known as endometrial cancer) and cervical cancer. Globally, more than 200,000 women die from cervical cancer each year. In developing countries, cervical cancer is a common and frequent gynecological tumor, ranking first. So what are the causes of uterine cancer? 1. Obesity: About 80% of endometrial cancer patients weigh more than 10% of the normal average body weight. Obesity is a manifestation of endocrine imbalance. A large amount of fat in the body increases the storage of estrogen. Fat is also conducive to the aromatization of androgens, increasing the estrogen content in the blood, leading to endometrial hyperplasia and even cancer. 2. Infertility is a high-risk factor for endometrial cancer. The risk decreases with the increase in the number of births. Women with infertility caused by long-term anovulation are more likely to suffer from this disease than women who have given birth to one child. Patients with polycystic ovary disease are also prone to this disease for the same reason. 3. Those with menstrual disorders, early menarche or delayed menopause are more susceptible to endometrial cancer. In the period before menopause, there is often no ovulation, estrogen has no progesterone to counteract, and the endometrium proliferates. 4. It is related to eating habits. People who consume a lot of fat and oil have an increased relative risk of endometrial cancer, while vegetables and fruits have a protective effect, reducing the relative risk. High fat has the function of storing estrogen, which will cause endometrial hyperplasia and even transformation into cancer. 5. Some patients with diabetes, hypertension, etc. may have high estrogen levels in their bodies due to long-term pituitary abnormalities; women with polycystic ovary syndrome and atypical endometrial hyperplasia may have high estrogen levels in their bodies due to long-term pituitary abnormalities. 6. For various reasons, those who take exogenous estrogen for a long time have an increased possibility of developing endometrial cancer. Using exogenous estrogen alone without progesterone can increase the risk of endometrial cancer, which is related to the dose and duration of estrogen. If progesterone is added to counteract it, the risk can be reduced. 7. For uterine bleeding that does not heal for a long time, especially uterine bleeding after menopause, you should consider the possibility of endometrial cancer and have a gynecological examination as soon as possible for early detection and treatment. 8. People with high income and higher education have a 2 times higher risk of developing endometrial cancer than poorer people. 9. Those with a history of X-ray exposure have a higher probability of developing endometrial cancer than those without a history of X-ray exposure. Due to the influence of genetic factors, patients with endometrial cancer often have a family history or a history of cancer in close relatives. Therefore, those with a family history of endometrial cancer and a history of cancer in close relatives have an increased risk of the disease. |
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