Early treatment methods for uterine cancer

The harm of endometrial cancer is very serious. Many women will be harmed and their lives will be affected. Therefore, friends should understand endometrial cancer clearly and pay attention to the treatment of this disease. The following will introduce to friends what methods can be used to treat endometrial cancer.

Combined treatment of surgery and radiation. Intracavitary radiotherapy is generally used, and external irradiation is used in a few cases. For example, if the volume is larger than the uterus of a 3-month pregnancy, the preoperative irradiation dose should not be large, and the general tissue volume is 20-30Gy. Preoperative intracavitary full-dose irradiation The intracavitary radiotherapy dose at point F is 50Gy±10, and at point A is 45Gy±10% or both are 50Gy±10. Full hysterectomy + adnexectomy is performed 8 to 12 weeks after the end of radiotherapy. Preoperative intracavitary non-full-dose irradiation Intracavitary radiotherapy is given 3 to 4 times/3 weeks before surgery, with a total dose of 25Gy to 30Gy at points F and A. Full hysterectomy + adnexectomy is performed 7 to 14 days after surgery. Postoperative radiotherapy.

Postoperative external irradiation For patients who received intracavitary radiotherapy before surgery, those with lymph node metastasis or suspected lymph node metastasis during surgical exploration, those with myometrial infiltration exceeding 1/3 of the inner layer and adenocarcinoma G2, G3, adenosquamous carcinoma, papillary adenocarcinoma, clear cell adenocarcinoma, and papillary serous adenocarcinoma should be given additional irradiation after total hysterectomy. Generally, the whole pelvic cavity is irradiated, with the same field as the whole pelvic cavity field for cervical cancer, and the dose is 50Gy. Postoperative intracavitary irradiation For patients who have cancerous tissue at the vaginal margin or the margin is adjacent to cancerous tissue during postoperative specimen examination, intracavitary radiotherapy should be given after surgery. The vaginal surface dose is 20Gy to 25Gy, which can be given in 3 to 7 times and completed within 2 weeks. For chemotherapy, it is currently mainly an adjuvant treatment for patients with poor prognosis and easy recurrence. Chemotherapy can be performed for patients with special pathological types of endometrial cancer and those who indicate distant metastasis.

In principle, as long as the patient's physical condition can tolerate it, they should receive surgical treatment as soon as possible, unless the patient has serious medical complications and cannot tolerate surgery, or the disease is already in the advanced stage and surgical resection is estimated to be difficult to perform. Surgery can make a correct diagnosis and staging, which is directly related to further treatment and prognosis after surgery.

Therefore, accurate clinical staging is the guarantee for choosing appropriate treatment methods, otherwise it is very likely to lead to excessive or insufficient treatment. Endometrial cancer is sensitive to radiotherapy, so radiotherapy is the preferred adjuvant treatment after surgery. Radiotherapy can reduce the local recurrence rate of patients with moderately differentiated endometrial cancer and improve the 5-year survival rate of patients with highly differentiated endometrial cancer. If the patient is in poor physical condition, cannot tolerate surgery, or is unwilling to undergo surgical treatment, radiotherapy is the first choice. Surgery can remove the cancerous uterus and other lesions that may have metastasized, including closely adjacent ovaries, fallopian tubes, and surrounding lymph nodes. Through surgery, the tumor can be directly eradicated to achieve the purpose of cure, or the tumor volume can be reduced to benefit the patient's prognosis.

The above knowledge introduces the methods of treating endometrial cancer. This disease is common among female friends and it will bring considerable pain to patients. Therefore, we must pay attention to endometrial cancer and carry out relevant treatments when the disease occurs. I hope that all women will pay attention to the treatment measures of this disease.