What are the methods for treating uterine cancer

Endometrial cancer is a particularly common gynecological disease. It has a great impact on people's physical and mental health, and it will also affect the health of the majority of female friends and their work. There are many ways to treat endometrial cancer. The most common one is surgery. Let's learn more about these treatments!

1. Surgical treatment is the preferred method. For stage I patients, extrafascial total hysterectomy and bilateral adnexectomy are performed, and for stage II patients, extensive total hysterectomy and pelvic lymph node dissection should be performed. Surgery can remove the cancerous uterus and other lesions that may have metastasized, including the closely adjacent ovaries, fallopian tubes, and surrounding lymph nodes. Through surgery, the tumor can be directly eradicated to achieve the purpose of cure, or the tumor volume can be reduced to benefit the patient's prognosis. Second, surgery can correctly diagnose and stage the disease. Although most patients with endometrial cancer have undergone segmented curettage, the error rate of pathological type and degree of differentiation between curettage specimens and specimens after hysterectomy is as high as 20%, and these indicators are directly related to further treatment and prognosis after surgery. Therefore, accurate clinical staging is a guarantee for choosing appropriate treatment, otherwise it is very likely to lead to excessive or insufficient treatment.

2. Combined surgery and radiation therapy: For patients in stage I, if cancer cells are found in the ascites or the myometrium is infiltrated, and there is lymph node metastasis, external irradiation is given after surgery. For patients in stage II or some stage III, external irradiation or intracavitary irradiation is given before surgery, and surgery is performed 1 to 2 weeks after the end of radiotherapy.

3. Radiotherapy: The elderly, frail patients, patients with severe medical complications who cannot tolerate surgery, and patients in stage III or above who are not suitable for surgery can be treated with radiotherapy, including intracavitary and external irradiation.

4. Hormone therapy Young patients in the early stage who want to retain their fertility, patients with advanced cancer who cannot undergo surgery or with cancer recurrence can be treated with large doses of synthetic progesterone, such as 400 mg of medroxyprogesterone acetate, intramuscular injection, 2 to 3 times a week; 500 mg of progesterone acetate, intramuscular injection, 2 to 3 times a week, etc. The efficacy can be evaluated after at least 12 weeks.

5. The anti-estrogen drug tamoxifen has the same indications as progestin therapy. The general dose is 20-40 mg/d, taken orally. It can be used for a long time or in divided courses.

6. For advanced cases that cannot undergo surgery or radiotherapy, or those that relapse after treatment, anti-cancer chemotherapy can be combined with chemotherapy such as 5-fluorouracil (5-Fu), cyclophosphamide (CTX), mitomycin (MMC), doxorubicin (BDR), and cisplatin (DDP), which has a certain effect.

The above content is about the treatment of endometrial cancer. Here we recommend that female friends who suffer from endometrial cancer must choose a treatment method that is more suitable for them according to their condition and physical condition. When they discover the disease, they must make a positive and decisive choice and do not delay.