What is the inheritance probability of esophageal cancer

There is no completely unified conclusion on the heritability of esophageal cancer. However, its heritability is not manifested in the cancer itself, but only in the tendency (or susceptibility) to develop tumors. On this basis, coupled with the role of carcinogenic factors in the acquired environment, a tumor can only be produced after a complex carcinogenesis process. "In other words, the heritability of esophageal cancer is only a possible factor in its occurrence.

Long-term eating habits and preferences are the main causes of the disease. People in the same family have very similar eating habits, so the family clustering phenomenon is high. Men have a long-term habit of smoking and drinking strong alcohol, and they eat hard food without chewing it carefully, which is related to the high incidence of esophageal cancer.

Esophageal cancer is caused by a certain proportion of genetics. There is a certain family clustering among people suffering from esophageal cancer. For example, people from high-incidence areas migrate to low-incidence areas, but the incidence rate of this group of people is still high compared with the local population. This proves that genetics accounts for a certain proportion.

It is currently believed that esophageal cancer is not a direct hereditary disease, but many cases of esophageal cancer tend to cluster in families. If someone in the family has esophageal cancer, his children are several times more likely to have esophageal cancer than the average person. These cancers are called hereditary familial cancers. The influence of this genetic factor is medically called genetic susceptibility.

Through observation, people gradually realized that lifestyle and exposure to certain carcinogens in the environment can increase the body's susceptibility to esophageal cancer. It was also found that some patients with congenital immune deficiencies have a much higher risk of esophageal cancer than normal people. For hereditary familial esophageal cancer, those who often have defective genes are more likely to develop esophageal cancer. A large amount of clinical data confirms that if there is an esophageal cancer patient in the family, the offspring will not necessarily develop esophageal cancer.

In addition, very few esophageal cancer families have been found in the world. In such families, about one-third of the members have successively suffered from esophageal cancer, and the incidence rate is the same for men and women, and they mostly suffer from the same type of cancer. Such esophageal cancer families are definitely related to genetics, but in fact, there are not many such families.

The genetic problem of esophageal cancer is very complicated. The occurrence of esophageal cancer is a mystery that has not yet been fully solved. Therefore, when someone in your family has cancer, you must not be crazy, but stay in a good mood, improve your immunity, learn and understand the relevant knowledge of esophageal cancer, and help your family and friends build confidence in defeating cancer.