What's the matter with the two plus signs in occult blood

No matter how our lives are, only our good health is the foundation of all happiness. However, due to various factors, people are prone to various diseases. When many people undergo examinations, two plus signs of occult blood appear on their test reports, and they are not very clear about what is going on with them. So, what do the two plus signs in occult blood mean? Let’s take a closer look at it.

If there are more than 2 red blood cells per high-power field of view in the urine after centrifugation under a microscope, it is called hematuria. Under a high-power microscope, 10 red blood cells are counted as "+, 1+ or +1", 20 are counted as "++, 2+ or +2", 30 are counted as "+++, 3+ or +3", and 40 are counted as "++++, 4+ or +4". In other words, the more plus signs there are, the more severe the damage to the kidney's intrinsic cells. For example, occult blood +2 means that 20 red blood cells were found under a high-power microscope after the urine was centrifuged.

The appearance of “+” indicates that the intrinsic cells of the kidney have begun to be damaged, and the filtration function of the kidney has begun to be impaired by the immune mediator complex. If it is not effectively treated, the number of damaged and proliferating glomeruli will increase, and the degree of kidney damage will gradually increase. At this time, we should receive systematic and regular treatment to effectively inhibit the development of renal fibrosis.

The treatment of urine occult blood 2+ caused by kidney disease needs to start from the root cause of the disease in order to achieve a quick cure. Renal fibrosis is a pathophysiological change, which is a gradual process in which the kidney function changes from healthy to damaged, then to damaged, and finally to loss of function.

The reason for the appearance of occult blood in urine is that under the action of kidney inflammation, the kidney's intrinsic cells are damaged, the glomerular filtration barrier is destroyed, and the ability to prevent the leakage of large molecular red blood cells is reduced. Under the action of the damaged filtration barrier, blood cells are leaked into the urine, and occult blood in the urine appears clinically.

The above is an introduction to what the two plus signs mean for occult blood. I hope it will be helpful to everyone’s understanding. When conducting a physical examination, if two plus signs appear for occult blood, it means that the condition is still somewhat serious. It is best to conduct further detailed examinations to determine the condition, and then take effective measures to treat it to avoid more serious consequences to our health.