In the past five years, radiofrequency ablation technology has been widely used in the comprehensive treatment of liver cancer, and rich experience has been accumulated. With the significant improvement of radiofrequency ablation equipment and the deepening of people's understanding of liver cancer, some carefully selected patients with large liver cancer have achieved good clinical results through comprehensive treatment mainly based on radiofrequency ablation. Combined application of transarterial chemoembolization Rich arterial blood supply is the most important pathophysiological feature of liver cancer. These abundant arterial blood vessels can take away the heat in the ablation focus, thus affecting the efficiency and efficacy of radiofrequency ablation. This is especially true for radiofrequency treatment of large liver cancer. The application of transarterial interventional chemoembolization before radiofrequency ablation can effectively reduce the arterial blood supply in liver cancer and improve the efficiency and efficacy of radiofrequency ablation. Laparoscopic radiofrequency ablation Large liver cancer is often closely related to important structures such as the diaphragm, gallbladder, colon, stomach and duodenum. Therefore, it is difficult to use percutaneous puncture and is prone to complications such as damage to important structures. Laparoscopy can provide a clearer, more intuitive and comprehensive field of view, and the puncture angle is more flexible and applicable, which significantly improves safety. Repeated radiofrequency ablation Large liver cancers often require multiple radiofrequency ablations. Modern studies have shown that repeated radiofrequency ablation can enhance the body's anti-tumor immune function. During the first radiofrequency ablation, tumor cells and some normal liver cells degenerate and necrotize, and a large number of autoantigen components enter the blood, which can activate tumor-specific T lymphocyte responses. Repeated radiofrequency ablation in a short period of time causes a large number of autoantigen components to enter the blood again, and T lymphocytes proliferate in large numbers, which significantly enhances the body's anti-tumor immune function. Pain-free guarantee and breathing support Radiofrequency ablation treatment for large liver cancer can last more than 2 hours. General anesthesia and respiratory support can eliminate the patient's tension and pain, thereby eliminating the patient's tension. |
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