Bad habits and chronic diseases cause pancreatic cancer

With the increasing incidence of pancreatic cancer, it is urgent to find out its root causes. Among the many risk factors, bad habits and chronic diseases are important causes of pancreatic cancer.

Bad habits can lead to pancreatic cancer

1. Long-term coffee drinking: Studies have shown that coffee can inhibit DNA repair and induce mitosis before DNA replication is completed, which is the main cause of pancreatic cancer.

2. Alcoholism: Studies have shown that people of different races have different rates of pancreatic cancer after drinking. Data show that compared with white people, black male alcoholics and female moderate drinkers have a higher incidence of pancreatic cancer.

3. Smoking: A large number of studies support the close connection between pancreatic cancer and smoking, and maintaining adequate folic acid and pyridoxal levels can reduce the risk of pancreatic cancer related to smoking.

Chronic disease progresses to pancreatic cancer

1. Chronic pancreatitis: Pancreatic cancer is related to chronic pancreatitis. Most of the results of epidemiological and molecular epidemiological studies support the view that chronic pancreatitis can develop into pancreatic cancer.

2. Diabetes: The occurrence of pancreatic cancer may also be related to diabetes. Experimental studies have shown that insulin can promote the growth of pancreatic cancer cells in vitro or in vivo; high concentrations of insulin can activate the insulin-like growth factor-1 receptor, producing a growth-promoting effect including changes in the cell cycle process.