The main pathogenesis of colorectal cancer

The main pathogenesis of colorectal cancer

Colorectal cancer is a malignant tumor that occurs in the intestinal mucosa. Because the early symptoms of colorectal cancer are not obvious, they are easily ignored. By the time abnormalities are discovered, most of the time the cancer is in the late stage, which makes the treatment of the disease very difficult. Therefore, we remind everyone not to ignore some minor symptoms.

The pathogenesis of bowel cancer is as follows:

In the earliest stage, food absorption is normally mainly completed in the small intestine. By the time food reaches the colon and even the rectum, it has become waste for excretion. After people chew food, it passes through the small intestine first to the right colon, then to the left colon, and finally to the rectum. When food residues reach the right colon, some liquid is still not completely absorbed. At this time, the intestinal contents are liquid. Because the right colon is wider, obstruction rarely occurs. However, this type of tumor is often characterized by secondary infection and chronic toxin absorption. Therefore, patients with right-sided colon cancer often have symptoms such as low-grade fever, night sweats, general fatigue, and anemia.

When food residues reach the left colon, they become completely unabsorbable residues, and the original liquid state becomes semi-solid. Since the intestinal cavity of the left colon is narrower, the smaller intestinal cavity quickly becomes narrow, so it is easy to have symptoms of low intestinal obstruction such as abdominal distension, abdominal pain, and constipation.

The rectum is located at the end of the digestive tract. Early rectal cancer lesions are only on the intestinal mucosa and may have no obvious symptoms. However, as the condition gradually worsens, there may be local irritation symptoms of the tumor. The patient will have an increase in the frequency of bowel movements, from the normal 1 to 2 times a day to 3 to 4 times or even more, with unformed stools, and constipation and diarrhea may also occur alternately. The patient feels discomfort in the anus, a feeling of falling, sometimes dull pain in the abdomen, and sometimes bloody and mucus in the stool. Only then did the patient realize that the situation was not good and went to see a doctor, but was diagnosed with advanced intestinal cancer.

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