It is important to understand the pathogenesis of gastric cancer

The pathogenesis of gastric cancer is very complex and the process is long, which can last for decades. It often progresses from chronic superficial gastritis to atrophic gastritis, followed by intestinal metaplasia leading to dysplasia and ultimately leading to gastric cancer.

Normal gastric mucosal epithelial cells are formed by the continuous division, growth and differentiation of stem cells. Their growth and death are controlled by the body. They will not grow out of control, will not form carcinogens, and therefore cannot develop into gastric cancer cells.

The pathogenesis of gastric cancer is induced by internal and external factors. Internal carcinogenic factors are mainly manifested as the expression of proto-oncogenes in hereditary family history. External carcinogenic factors can directly induce or long-term damage the gastric mucosal barrier, making it easier for carcinogens to induce stem cell oncogene expression or gene mutation to produce carcinogens, turning newly born immature primitive cells into various abnormal cells with poor differentiation and uncontrolled growth.

If the patient's immune monitoring function is normal, a small amount of abnormal cells can be cleared. However, if the patient's mental state is not good for a long time, it is likely to lead to abnormal endocrine system and long-term low immune function, or abnormal cells escape the body's immune monitoring for some unknown reason, and eventually develop into gastric cancer cells whose growth cannot be controlled by the body, completing the cancer process. Once cancer cells are formed, they will explosively grow into gastric cancer lesions visible to the naked eye. Depending on the patient's age and growth and metabolic rate, this process may take half a year to several years.

The local lesions of gastric cancer continue to grow, gradually occupying the space of normal gastric cells and causing the normal function of the stomach to weaken, and even directly infiltrating into adjacent tissues and organs. When the local cancer lesions grow wildly and break through the gastric serosa and scatter into the abdominal cavity and implant in various parts of the abdominal cavity, cancer cells in various parts of the body will grow wildly and uncontrollably, constantly robbing normal cells of nutrients, and eventually causing normal tissues and organs to fail due to extreme malnutrition and eventually face death.