What is the main cause of colorectal cancer?

Among cancer diseases, colorectal cancer is a common and high-incidence one. In order to avoid the occurrence of colorectal cancer, we should learn more about the causes of colorectal cancer in our daily life. Let's learn about it together from the following article.

1. Colon adenoma is one of the causes of colon cancer. The incidence of colon adenoma is quite consistent with that of colon cancer. According to statistics, the incidence of colon cancer in patients with one adenoma is 5 times higher than that in patients without adenoma, and the incidence of colon cancer in patients with multiple adenomas is 1 times higher than that in patients with a single adenoma.

2. The cause of colorectal cancer is related to chronic colorectal inflammation. The risk of colorectal cancer in patients with chronic ulcerative colitis is 4 to 20 times higher than that in normal people. The risk of sudden malignant transformation in hemorrhagic ulcerative colitis is even greater. For patients with a disease course of more than 10 years, 50% will develop colorectal cancer.

3. Dietary factors can also easily lead to the occurrence of colorectal cancer. Studies have shown that among various environmental factors, dietary factors are the most important. A large number of studies have shown that the incidence of colorectal cancer is positively correlated with the fat consumption in the food, and negatively correlated with the intake of vegetables and cellulose. A high-fat diet can increase the concentration of neutral cholesterol and bile acid in the large intestine, and affect the composition of intestinal bacteria that act on these products. Bile acid and neutral cholesterol have a similar three-dimensional structure to polycyclic aromatic hydrocarbons, and their degradation products also have carcinogenic or auxiliary carcinogenic effects.

The above are the main causes of colorectal cancer. I believe you can have a comprehensive understanding of this aspect of colorectal cancer. If you have other questions about colorectal cancer, you can contact our online experts to answer your questions.