An introduction to the causes of colorectal cancer that everyone needs to know

The causes of colorectal cancer are relatively complex. The causes of colorectal cancer in different people may be different. In-depth research is needed to finally determine the cause of colorectal cancer, which is very important for the treatment of colorectal cancer. So what are the common causes of colorectal cancer ? Let's talk about the common causes of colorectal cancer.

In general, the common causes of bowel cancer are:

1. History of inflammatory bowel disease: Certain bowel diseases such as Crohn's disease or ulcerative colitis may increase the chance of developing colorectal cancer. Their risk of colon cancer is 30 times that of ordinary people. This is a common cause of bowel cancer.

2. History of colorectal polyps: Most colorectal cancers develop from small precancerous lesions, which are called polyps and are also a common cause of colorectal cancer. Among them, villous adenomatous polyps are more likely to develop into cancer, with a chance of malignant transformation of about 25%; the malignant transformation rate of tubular adenomatous polyps is 1-5%.

3. Genetic background: Familial adenomatous polyposis and hereditary non-polyposis colorectal cancer are caused by mutations in the corresponding genes. These patients not only have a significantly increased risk of developing the disease, but also develop it at a younger age.

4. Age: As age increases, the time that various pathogenic factors stimulate the colon mucosa also increases, and most patients develop the disease after the age of 50. This is a common cause of colon cancer.

5. Family history: If a person's first-degree family member, such as a parent, has had colorectal cancer, his risk of developing the disease in his lifetime is 8 times higher than that of the general population [If one of your direct family members (parents, siblings or children) develops colorectal cancer before the age of 50, or if two or more people in your paternal or maternal family have colorectal cancer, then you have a family history of colorectal cancer]. About 1/4 of new patients have a family history of colorectal cancer, which is also a cause of colorectal cancer.

The above is an explanation of the common causes of colorectal cancer. I believe everyone should have a certain understanding of this. If you have any questions, you can contact our online experts, who will give detailed answers based on the patient's specific situation.