Analyzing the causes of bladder cancer that everyone needs to understand

In recent years, more and more people in China have been suffering from bladder cancer. Most bladder cancer patients are confused about why they have bladder cancer and have almost no understanding of the cause of bladder cancer, which has brought certain adverse effects on the treatment of bladder cancer. What are the common causes of bladder cancer ? Let's talk about the common causes of bladder cancer.

Common causes of bladder cancer include:

1. People who work with long-term contact with aromatic substances, such as dyes, leather, rubber, and painters, may have a high incidence of bladder tumors. This is a common cause of bladder cancer.

2. Abnormal tryptophan metabolism in the body is also a common cause of bladder cancer. Abnormal tryptophan metabolism can produce some metabolites, such as 3-hydroxy-2-aminoacetophenone and 3-hydroxy-o-aminobenzoic acid, which can directly affect the synthesis of RNA and DNA in cells. These metabolites are excreted into the bladder through the action of the liver and have a carcinogenic effect after being acted on by &beta-glucuronidase.

3. Smoking is also a cause that increases the incidence of bladder cancer. Recent studies have shown that smokers increase the metabolism of the carcinogenic substance tryptophan in their urine by 50%. When smoking stops, tryptophan levels return to normal. This is a common cause of bladder cancer.

4. Long-term local irritation of the bladder mucosa and the bladder wall, such as long-term chronic infection, long-term irritation of bladder stones and urinary tract obstruction, may be the cause of bladder cancer. Glandular cystitis and mucosal leukoplakia are considered to be precancerous lesions that can induce cancer.

The above analysis is about the common causes of bladder cancer. I believe everyone should have some understanding of this. If you still have questions about the causes of bladder cancer, you can consult our online experts, who will answer you in more detail.