What causes bladder cancer?

Bladder cancer is the most common malignant tumor in the urinary system. Many factors in life are the cause of bladder cancer. So, what are the causes of bladder cancer? Let's take a look at how experts answer the question of the causes of bladder cancer .

The main causes of bladder cancer are:

1. Workers who are in long-term contact with aromatic substances, such as dyes, leather, rubber, painters, etc., may have a high incidence of bladder tumors.

2. Smoking: It is also a cause that increases the incidence of bladder tumors. Recent studies have shown that smokers increase the metabolism of the carcinogenic substance tryptophan in their urine by 50%. When smoking stops, tryptophan levels return to normal.

3. Drugs: Taking large amounts of phenacetin drugs has been proven to cause bladder cancer.

4. Parasitic diseases: If they occur in the bladder, they can also induce bladder cancer.

5. Abnormal tryptophan metabolism in the body: Abnormal tryptophan metabolism can produce some metabolites, such as 3-hydroxy-2-aminoacetophenone and 3-hydroxy-o-aminobenzoic acid, which can directly affect the synthesis of RNA and DNA in cells. These metabolites are excreted into the bladder through the liver and have carcinogenic effects after being acted on by β-glucuronidase.

6. Long-term local irritation of the bladder mucosa: Long-term local irritation of the bladder wall, such as long-term chronic infection, long-term irritation of bladder stones and urinary tract obstruction, may be factors that induce cancer. Glandular cystitis and mucosal leukoplakia are considered to be precancerous lesions that can induce cancer.

The above are the causes of bladder cancer. Through the introduction of experts, I believe you have a certain understanding of the causes of bladder cancer. If you have any questions about the causes of bladder cancer, please consult our online experts.

For more information, please visit the bladder cancer disease special topic at http://www..com.cn/zhongliu/pg/ or consult an expert for free. The expert will then give a detailed answer based on the patient's specific situation.