What are the extrapulmonary symptoms of lung cancer?

We know that the typical symptoms of lung cancer are cough, blood in sputum, chest pain, shortness of breath and other lung manifestations; however, according to statistics, about half of lung cancer patients initially show symptoms outside the lungs, and these symptoms often appear before the lungs, which invisibly become early signs of lung cancer. So what are the extrapulmonary symptoms of lung cancer?

Extrapulmonary symptoms of lung cancer 1. Bone and joint symptoms: These symptoms are more common. Lung cancer cells can produce certain special endocrine hormones (xenohormones), antigens and enzymes, which act on the bone and joint parts, causing bone and joint swelling and pain, often involving the tibia, fibula, ulna, radius and other bones and joints. The ends of the fingers and toes often swell and become clubbed, and X-ray examinations can show periosteal hyperplasia.

Extrapulmonary symptoms of lung cancer 2. Shoulder and back pain: Peripheral lung cancer often develops posteriorly and upwards, eroding the pleura, involving the ribs and chest wall tissue, thus causing shoulder and back pain. Such patients rarely have respiratory symptoms.

Extrapulmonary symptoms of lung cancer 3. Hoarseness: Lung cancer metastasis compresses the laryngeal nerve, which can cause vocal cord paralysis and hoarseness. Since lung cancer metastasis can appear in the early stage and sometimes grow faster than the primary lesion, the clinical manifestations of metastasis can appear before the primary lesion.

Extrapulmonary symptoms of lung cancer 4. Neurological symptoms: Brain metastasis of lung cancer may cause neurological symptoms such as headache, vomiting, sudden coma, aphasia, hemiplegia, etc. Because the lung symptoms are not obvious, they are often misdiagnosed as thrombosis and brain tumors.

Extrapulmonary symptoms of lung cancer 5. Male breast hypertrophy: About 10%-20% of male lung cancer patients have breast hypertrophy, some have unilateral hypertrophy, but most have bilateral hypertrophy, and this symptom appears about a year earlier than other lung symptoms such as cough, blood in sputum, chest pain, and shortness of breath. This is because some lung cancer cells can secrete chorionic gonadotropin, which can cause breast tissue hyperplasia and breast hypertrophy.

The above are the extrapulmonary symptoms of lung cancer. These symptoms have nothing to do with lung cancer and are often mistaken for other diseases. Therefore, we must be more vigilant. Mastering these signals will be helpful for early diagnosis and treatment.

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