How does gallbladder cancer metastasize and spread

In recent years, gallbladder cancer has become one of the major diseases that endangers society and human health, and it has brought great pain and distress to humans. In order to reduce the incidence of gallbladder cancer, we humans should understand the metastasis and spread of gallbladder cancer:

Gallbladder cancer develops and grows rapidly, and is prone to early spread. There are three ways of metastasis: lymphatic metastasis, hematogenous metastasis, and direct infiltration. Some people have found through surgery that among patients with gallbladder cancer that have metastasized, about 25%-75% have metastasized through the lymphatic tract; more than half of the cancers can directly infiltrate adjacent organs, in the order of metastasis: liver, bile duct, pancreas, stomach, duodenum, omentum, colon, and abdominal wall; about 1/5 (13%-19%) of patients have metastasis through the blood.

Gallbladder cancer is a common metastatic route through the lymph nodes and directly to the liver. When the cancer grows extensively beyond the mucosa, perineural and vascular metastasis may also occur.

Gallbladder cancer can extend downward and cause bile duct obstruction. About 25% of gallbladder cancers can penetrate and spread to adjacent organs, including the stomach, duodenum, colon, and peritoneum. Distant hematogenous metastases often involve the lungs, bones, and kidneys. Patients with gallbladder cancer often have enlarged Virchow nodes on the clavicle.

The above is the metastasis and spread of gallbladder cancer. Expert Tip: If you have symptoms of disease, do not delay diagnosis and go to a regular hospital for treatment in time to avoid delaying the disease and causing serious consequences. If you have other questions, please consult our online experts or call for consultation.

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