What is the role of albumin infusion

What is the role of albumin infusion

The blood in the human body has many components, including hemoglobin, white blood cells, red blood cells, plasma, etc., and the largest component of plasma is albumin, which is very important for maintaining blood pressure stability and regulating the body's metabolism. If you need to undergo albumin infusion surgery, it means that the patient is experiencing problems with low plasma concentration and insufficient nutrient transport by plasma.

What does albumin do?

Physiological effects

(1) Maintaining a constant plasma colloid osmotic pressure

Albumin is a protein with the largest content in plasma, the smallest molecule, the highest solubility, and the most functions. Edema.

(2) Transport function of plasma human albumin

Plasma albumin can reversibly combine with many poorly soluble small molecular organic substances and inorganic ions in the body to form highly soluble complexes, which become the transport form of these substances in the blood circulation. This shows that albumin is a non-specific transport protein, which is physiologically important and closely related to human health. Human serum albumin is suitable for the prevention and treatment of hypoproteinemia, and the treatment of edema or ascites caused by cirrhosis and kidney disease.

(3) Other physiological effects of plasma albumin

The albumin content in plasma is much higher than that of globulin, and its hydrophilic effect is greater than that of globulin, which makes the albumin in plasma play a colloidal protective and stabilizing role on globulin. When liver dysfunction causes insufficient albumin synthesis, plasma globulin may lose its colloidal protective effect and its stability may decrease. The decreased stability of plasma globulin will seriously affect the metabolism and utilization of these substances in the body, causing corresponding symptoms. In addition, albumin is an important nutrient in the human body. Albumin is also constantly metabolized and renewed in the plasma. The amino acids produced by the decomposition of plasma albumin can be used to synthesize tissue proteins, oxidized and decomposed to supply energy, or converted into other nitrogen-containing substances.

When active hormones or drugs are bound to albumin, they may not show their activity and be considered as their storage form. Due to the reversibility and dynamic equilibrium of this binding, it is of great significance in regulating the metabolism of these hormones and drugs.

Albumin is a viscous, gelatinous substance. When it encounters heavy metal ions in the human body, it will automatically combine with the heavy metal ions and be excreted from the body through the excretory system, thus playing a detoxifying role. Therefore, eating foods rich in albumin can avoid poisoning caused by the absorption of heavy metal ions. Albumin also has a protective effect on the stomach wall.

Human albumin is a type of blood product, commonly known as "life product" and "life-saving medicine." It is extracted from the blood of healthy people and injected directly into the patient's body intravenously. Its main function is to enhance human immunity and resistance. The market price is 300 to 400 yuan per bottle. Clinically, it is mainly used to treat critical illnesses such as shock and cerebral edema caused by blood loss, trauma and burns, edema or ascites caused by cirrhosis and kidney disease, and patients with hypoproteinemia.

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