Will focal liver hyperplasia disappear?

Many people may not know the cause and symptoms of focal hepatic hyperplasia, so many people mistakenly believe that this liver disease will disappear automatically. In fact, this disease is caused by hyperplasia of the liver, which may be caused by inflammatory infection. However, if it is not treated in time, it will develop into cirrhosis or hepatitis. It is recommended that patients learn about the treatment methods of focal hepatic hyperplasia.

Causes

It is currently believed that FNH is a proliferative response of the liver parenchyma to congenital arterial malformations, or is related to localized blood supply reduction caused by inflammation, trauma, etc., rather than a true tumor. Clinically, FNH is occasionally associated with vascular abnormalities such as hemangiomas, which also supports the theory of congenital vascular abnormalities. Some researchers also believe that the onset of FNH may be related to estrogen.

Clinical manifestations

The vast majority of FNH patients have no clinical symptoms, and less than one-third of patients seek medical treatment due to mild upper abdominal pain or abdominal masses. FNH is usually discovered incidentally during laparotomy or physical examination.

Symptomatic patients may present with right upper quadrant abdominal pain or discomfort, hepatomegaly, or a right upper quadrant abdominal mass. Physical examination may reveal a hard mass located below the right costal margin or in the right upper abdomen, which is tender, has a smooth surface, and moves up and down with breathing.

treat

FNH is a benign lesion with no tendency to malignant transformation and rare complications. The following consensus has been reached on its treatment: observation and follow-up of FNH is safe, and surgery should be avoided once the diagnosis is clear; surgical resection is only performed when the tumor grows or the tissue diagnosis is unclear.

For FNH with a clear diagnosis and clinical symptoms, minimally invasive treatments such as arterial embolization, radiofrequency ablation, and high-intensity focused ultrasound can be used. For a small number of patients with huge tumors or multifocal FNH causing liver failure, liver transplantation may be considered.

For FNH discovered incidentally during laparotomy, the decision to perform surgery simultaneously should be made based on the size and location of the tumor, the patient's condition, and the surgeon's experience. For asymptomatic FNH, a simple liver biopsy is best performed. There is no consensus on the risk of complications of pregnancy and FNH, and there is no need for women who wish to become pregnant to undergo preventive resection.

Prognosis

This disease is benign and has a good prognosis. The lesions develop very slowly. There have been rare reports of nodule rupture, massive bleeding, death, and malignant transformation.