How to treat vitiligo

In people's daily lives, some diseases are inevitable. Diseases will not only threaten the patient's physical health, but also affect his life. There are many factors in life that can cause diseases. Vitiligo is a very common disease in daily life, but many people who have this disease do not know about the treatment of vitiligo. So, how to treat vitiligo?

First, how to treat vitiligo? Vitiligo is a common acquired localized or generalized skin depigmentation disease. It is caused by the disappearance of melanocyte function in the skin, but the mechanism is still unclear. It can occur in any part of the body, most commonly on the back of the fingers, wrists, forearms, face, neck, and around the genitals. It can also occur in the female vulva, mostly in young women.

Second, the cause of the disease is still unclear. Research in recent years believes that it is related to the following factors: Genetic theory says that vitiligo can occur in twins and families, indicating that heredity plays an important role in the onset of vitiligo. Studies have shown that vitiligo has incomplete penetrance and there are multiple pathogenic sites on the gene. According to the autoimmune theory, vitiligo can be combined with autoimmune diseases, such as thyroid disease, diabetes, chronic adrenal insufficiency, pernicious anemia, rheumatoid arthritis, malignant melanoma, etc. Specific antibodies to various organs can also be detected in the serum, such as anti-thyroid antibodies, anti-gastric parietal cell antibodies, anti-adrenal gland antibodies, anti-parathyroid antibodies, anti-smooth muscle antibodies, anti-melanocyte antibodies, etc. Psychological and neurochemical theory Psychological factors are closely related to the onset of vitiligo. Most patients suffer from mental trauma, excessive tension, depression or frustration during the onset or development of skin lesions. The degeneration of nerve endings in the white spots also supports the neurochemical theory. Melanocyte self-destruction theory: Antibodies and T lymphocytes can be produced in the bodies of vitiligo patients, indicating that the immune response may lead to the destruction of melanocytes. Toxic melanin precursors synthesized by the cells themselves and certain chemicals that cause skin depigmentation may also have a selective destructive effect on melanocytes. Trace element deficiency theory: The levels of copper or ceruloplasmin in the blood and skin of vitiligo patients are reduced, resulting in reduced tyrosinase activity, thus affecting the metabolism of melanin.

How to treat vitiligo? Hormone therapy, systemic treatment

It is mainly suitable for patients with generalized progressive vitiligo. Oral or intramuscular injection of hormones can stabilize progressive vitiligo as quickly as possible. (Local treatment: Topical glucocorticoids are effective for the treatment of localized vitiligo, but attention should be paid to the adverse reactions caused by long-term use of topical glucocorticoids. Commonly used drugs in clinical practice include halometasone ointment, mometasone furoate cream, etc.