How to use anti-inflammatory drugs for bronchial pneumonia

Bronchopneumonia is a disease mainly caused by lung infection. It is common in newborn babies. If not treated correctly, it may cause a series of problems such as chest tightness. It will not only affect the smoothness of the respiratory tract, but in severe cases it will also lead to other complications. So after bronchopneumonia occurs, can anti-inflammatory drugs be used to help recovery?

(1) Antimicrobial treatment

Principles: ① Select sensitive drugs according to the pathogen: Before using antimicrobial drugs, appropriate respiratory secretions should be collected for bacterial culture and drug sensitivity testing to guide treatment; before the culture results are obtained, sensitive drugs can be selected based on experience; ② The selected drugs should have a high concentration in lung tissue; ③ Early use of drugs; ④ Combination use of drugs; ⑤ Adequate dose and sufficient course of treatment. Children with severe cases should receive combined intravenous medication.

Antimicrobial treatment for community-acquired pneumonia (CAP) should be limited to bacterial pneumonia, mycoplasma pneumonia, chlamydial pneumonia, fungal pneumonia, etc. There is no indication for the use of antibiotics for simple viral pneumonia, but attention must be paid to the possibility of mixed infection with bacteria, viruses, mycoplasma, chlamydia, etc.

Children under 3 months old are likely to have Chlamydia trachomatis pneumonia, while those over 5 years old have a higher rate of Mycoplasma pneumonia and Chlamydia pneumoniae pneumonia. Therefore, macrolides are the first choice, especially the new generation of macrolides, which have a broad antibacterial spectrum and can cover most of the pathogens of CAP in children. When antimicrobial drugs are used to treat CAP in children aged 4 months to 5 years, especially in critically ill children, it should be considered that the pathogen is macrolide-resistant Streptococcus pneumoniae. High-dose amoxicillin or cephalosporin may be the first choice.

For fungal infections, antibiotics and hormones should be discontinued and nystatin nebulizer inhalation should be used. Clotrimazole, diflucan or amphotericin B can also be used.

(2) Antiviral treatment ① Influenza virus: Oseltamivir, zanamivir and panamivir are neuraminidase inhibitors, which are effective against both influenza A and B viruses. Amantadine and rimantadine are M2 membrane protein ion channel blockers that are only effective against influenza A virus. ② Ribavirin (viravirin) can be administered by nasal drops, nebulized inhalation, intramuscular injection, and intravenous drip, and can inhibit a variety of RNA and DNA viruses; α-interferon (IFN-α), a course of treatment is 5 to 7 days, and can also be nebulized inhaled. ③Ganciclovir, also known as ganciclovir, is the first-line drug for cytomegalovirus infection in children.