What are the four items of rheumatism

Going to the hospital for a check-up when you are sick is the most correct and fastest way. Diseases like rheumatism cannot be delayed for many years. The cause should be found and treated in time. Following your doctor's advice will also speed up the treatment of your condition. When you go to the hospital for a check-up, you will see a list of four rheumatism examination items. Most people don’t know what these four items specifically refer to. Let us understand what the four rheumatism items are.

1. How to read the four results of rheumatoid arthritis

Anti-"0": (ASO) titer is increased when it exceeds 200 units. Special reminder of recent hemolytic streptococcal infection. 80% of patients with acute rheumatic fever have elevated anti-"0", and patients with rheumatism and rheumatoid arthritis may have elevated levels.

Erythrocyte sedimentation rate: (ESR) 0-15mm/h for adult males and 0-20mm/h for adult females. Method: Adult males 0-10mm/h, adult females 0-12mm/h. An increased erythrocyte sedimentation rate indicates the presence of rheumatic activity; it may be normal in some patients and may also be normal when the condition is in remission.

Rheumatoid factor: (RF) The normal value of rheumatoid factor is 0-20. A value not exceeding 20 is considered clinically normal. Rheumatoid arthritis occurs in 70%-80% of adult patients. Children only account for about 30% of patients, and about 1%-5% of normal people are positive. A negative result cannot rule out rheumatoid arthritis and requires comprehensive clinical consideration.

C-reactive protein: (CRP) The normal value is generally less than 5ug/mg. If it is greater than 10ug/mg, it means that the rheumatic disease is in the active stage.

Rheumatoid arthritis is a systemic autoimmune disease. Clinically, the disease is often characterized by migratory pain in large joints, numbness in fingers, and aggravation by wind or cold. It may recur and affect the heart.

2. Causes of rheumatoid arthritis

The onset of RA may be related to genetics, infection, sex hormones, etc. The pathology of RA arthritis mainly includes proliferation of synovial lining cells, infiltration of a large number of inflammatory cells in the interstitium, new blood vessels, formation of pannus, and destruction of cartilage and bone tissue.

3. How to check rheumatoid arthritis

General examinations include blood and urine routine, erythrocyte sedimentation rate, C-reactive protein, biochemistry (liver and kidney function), immunoglobulin, protein electrophoresis, complement, etc.

Autoantibodies The detection of autoantibodies in RA patients is one of the hallmarks that distinguish RA from other inflammatory arthritis, such as psoriatic arthritis, reactive arthritis and osteoarthritis. Currently, the commonly used autoantibodies in clinical practice include rheumatoid factor (RF-IgM), anti-cyclic citrullinated (CCP) antibodies, rheumatoid factor IgG and IgA, anti-perinuclear factor, anti-keratin antibodies, as well as antinuclear antibodies and anti-ENA antibodies. In addition, it also includes anti-RA33 antibodies, anti-glucose-6-phosphate isomerase (GPI) antibodies, anti-P68 antibodies, etc.

Anti-hemolytic Streptococcus "O" (ASO), C-reactive protein (CRP), rheumatoid factor (RF) and erythrocyte sedimentation rate (ESR) are the four test items that distinguish between rheumatoid arthritis and rheumatism.