Vitiligo, also known as leukoplakia, is a disease caused by abnormal pigmentation. When vitiligo occurs, the condition can be well controlled as long as it is treated in time. There are many ways to treat vitiligo, such as hormone therapy, phototherapy, chemotherapy, transplantation therapy, immunosuppressants, vitamin D3 derivatives and other methods! 1. Hormone therapy (1) Systemic treatment is mainly suitable for patients with generalized progressive vitiligo. Oral or intramuscular injection of hormones can stabilize progressive vitiligo as quickly as possible. (2) Local treatment: Topical corticosteroids are effective in treating localized vitiligo, but attention should be paid to the adverse reactions caused by long-term use of topical corticosteroids. Commonly used drugs in clinical practice include halometasone ointment, mometasone furoate cream, etc. 2. Phototherapy and photochemotherapy (1) Phototherapy with narrowband ultraviolet (NB-UVB) has a certain effect in treating localized or generalized vitiligo. (2) Photochemotherapy (PUVA): For localized vitiligo, topical application of furanocoumarins (8-MOP, psoralea corylifolia tincture) + sun exposure is a good treatment option and can be used in adults and children over 5 years old. 3. Transplantation It is suitable for patients in the stable period, with few skin lesions in the past few days and no scarring constitution. Commonly used methods include autologous epidermal transplantation, microskin graft transplantation, autologous cultured melanocyte transplantation, etc. 4. Immunosuppressants For areas that are not suitable for the use of hormones, or to avoid adverse reactions from long-term use of hormones, topical calcineurin inhibitors (tacrolimus, pimecrolimus) have a certain effect. 5. Vitamin D3 derivatives Vitamin D3 derivatives can be combined with NB-UVB, PUVA, etc. for treatment. It can also be combined with topical corticosteroids and calcineurin inhibitors. 6. Prevention 1. Reduce the intake of contaminated food, correct picky eating, and develop a scientific diet recipe. 2. Reduce the inhalation of harmful gases and choose a place with fresh air when doing morning exercises or sports. 3. Pay attention to labor protection. 4. Pay attention to the pollution caused by house decoration. 5. Keep a happy mood. |
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