What is the normal ratio of albumin to globulin

The structure of the human body is very complex. In addition to the internal organs, there are also albumin and protein globulins in the blood. If there is a problem with the ratio of albumin to globulin in the human body, it will cause some physical diseases and other physical complications, which will cause great harm to the human body and seriously affect the patient's normal work and life. So what is the normal ratio of albumin to protein globulins? Let us take a look at it together below.

Albumin is produced in the liver. When liver function is severely impaired, albumin decreases, and the degree of decrease is parallel to the severity of hepatitis. Serum albumin concentration is reduced in patients with chronic and severe hepatitis and cirrhosis. Globulin is produced by the body's immune organs. When antigens such as viruses are present in the body, globulin production increases. Patients with chronic hepatitis and cirrhosis have decreased albumin production and increased globulin production, resulting in an inverted albumin/globulin (A/G) ratio. The A/G ratio is 1-2.5/1.

The normal human serum albumin concentration is greater than the globulin concentration. When the two are reversed, it may indicate liver and kidney diseases, certain autoimmune diseases and M proteinemia.

[Alias] White ball ratio

[English abbreviation] A/G

[Reference value] 1.5--2.5

Globulin is a simple protein that can be precipitated by 50% saturated ammonium sulfate solution. Insoluble in pure water, easily soluble in dilute salt water, and will precipitate or coagulate upon heating. Present in all animal and plant cells and body fluids. The most well-known globulin is human serum globulin, which can be separated by electrophoresis into α1-, α2-, β1-, β2- and γ-globulin, and is immunogenic. In addition, there are lactoglobulin, myosin, etc. Most of the proteins in plant seeds belong to this category. Globulin is generally insoluble in water, but can be dissolved by adding a small amount of salt, acid or alkali.

The above article describes the details of the normal ratio of albumin to globulin. I believe that after reading the above article, everyone has a detailed understanding of the normal ratio of albumin to globulin. I hope everyone will pay attention to their physical health in daily life, maintain good eating habits, and pay attention to reasonable food combinations.