In daily work and life, walking, running, jumping and other behaviors cannot be separated from the support of the feet. We have been accustomed to this for a long time, so we don’t think there is any problem. But when there is a problem with the feet, you will know how happy it is to move freely. For example, when your toes hurt when you walk, you will find that walking has become a painful thing. Then let’s talk about the reasons why your toes hurt like a needle prick when you walk. Polyneuritis is a general term for multiple peripheral nerve damage caused by various reasons such as poisoning, nutritional metabolic disorders, infection, allergies, and allergic reactions. The main clinical manifestations are symmetrical sensory, motor and autonomic dysfunction in the distal limbs. Causes: 1. Poisoning Such as heavy metals such as lead, arsenic, mercury, phosphorus, drugs such as furacillins, isoniazid, streptomycin, phenytoin sodium, carbamazepine, vincristine, and organic compounds such as organophosphorus pesticides. 2. Nutritional metabolic disorders Such as vitamin B deficiency, diabetes, uremia, chronic gastrointestinal diseases, pregnancy, etc. 3. Infection It is often accompanied or secondary to various acute and chronic infections, such as dysentery, tuberculosis, infectious hepatitis, typhoid fever, mumps, etc. In a few cases, it may be caused by direct invasion of peripheral nerves by pathogens, such as leprosy neuritis. 4. Allergies and allergic reactions Such as neuritis after serum treatment or vaccination. 5. Others Such as connective tissue diseases, hereditary diseases such as Charcot-Marie-Tooth disease, hereditary ataxia peripheral neuritis, hereditary sensory radiculoneuropathy, etc. In addition, various cancers of the body can also cause polyneuritis, and may occur several months before the primary lesion shows clinical symptoms, so this should be a cause for concern. Except for inflammatory changes in peripheral nerves caused by a few causes (such as leprosy), the pathological changes are mainly segmental demyelination and axonal degeneration of peripheral nerves, or both. A few cases may be accompanied by changes in the neuromuscular junction. |
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