The impact of bone marrow donation on the body

Bone marrow is a substance that plays an important role in the human body. It is generally located inside the bones and has a certain impact on the body's hematopoietic function. Many blood diseases are caused by bone marrow abnormalities. Many patients with blood diseases also need bone marrow transplants. Of course, if you want to have a bone marrow transplant, someone must first donate bone marrow. So, does donating bone marrow have any impact on the donor's body?

1. The impact of bone marrow donation on the body

Donating bone marrow generally has no effect on physical health and life expectancy. It is just that some drugs need to be used to stimulate the bone marrow before donation, and there will be discomfort when the bone marrow is drawn. There is no problem of failure, only the possibility of transplant failure in the recipient.

2. Bone Marrow Donation Procedures

Generally speaking, they include: ① physical and laboratory examinations; ② those who pass the physical examination fill out the relevant forms and sign the donation volunteer form; ③ the staff draws 5 ml of venous blood for tissue compatibility antigen (HLA) typing examination, and enters the examination data into the hematopoietic stem cell database; ④ when a patient needs hematopoietic stem cell transplantation, a matching donor is found in the hematopoietic stem cell database. If your information is the same as the patient's, then you can realize your wish to donate hematopoietic stem cells.

3. Impact of Bone Marrow Donation

Donating hematopoietic stem cells will not have any adverse effects on the donor's health. Many different types of blood cells in our body come from the same ancestor - the multipotent hematopoietic stem cell. Not only can it continuously differentiate into offspring, but it can also replicate cells that are exactly the same as itself. This ensures that our hematopoietic function continues uninterrupted. When old blood cells die, new ones grow to replace them; when some hematopoietic stem cells are damaged, healthy stem cells are quickly born to compensate. Our bodies work together so well. There are not many pluripotent stem cells, which are distributed throughout the bone marrow. When donating bone marrow, only a small part of the human body's bone marrow is extracted, and only a part of the pluripotent stem cells is lost. The remaining pluripotent stem cells will replicate rapidly, and the hematopoietic function will be completely restored to normal in a short period of time. Therefore, donating hematopoietic stem cells will not affect a person's hematopoietic function.