In our daily life, many people will have scars on their bodies due to some reasons. Many times, some scars will greatly affect the appearance, which will affect the self-confidence. Among the drugs for treating and relieving scars, the effect of compound heparin sodium allantoin gel is more obvious, so it is trusted by many scar patients. Of course, there are some things that need to be paid attention to when using this gel. Indications Hypertrophic scars and keloids; scars that restrict movement and affect appearance following surgery, amputation, burns, acne, and other accidents; contractures due to Dupuytren's contracture; tendon contractures and cicatricial strictures caused by trauma. Dosage 1. Apply this product to the scar area 3-4 times a day, and rub gently until the drug is completely absorbed. For old scars and hard scars, you can cover them with a dressing overnight after applying the medicine to allow the medicine to take full effect. 2. Depending on the size of the scar or contracture, the course of treatment often takes several weeks to several months. When treating acute scars, some physical stimuli should be avoided, such as excessive cold, UV radiation, or vigorous massage. Adverse Reactions This product is well tolerated and local skin irritation is uncommon. A small number of patients may experience mild itching, which generally does not affect continued treatment. No systemic adverse reactions. Drug Pharmacology 1. This product has the effects of anti-fibroblast proliferation, anti-inflammation and softening scar tissue. Onion extract has anti-inflammatory effects by inhibiting the release of inflammatory mediators, and also has anti-allergic effects. Onion extract can inhibit fibroblasts from various sources, especially those from scars. In addition to inhibiting their mitosis, it can also reduce the synthesis of extracellular matrix (such as proteoglycans). 2. Heparin has anti-inflammatory, anti-allergic, anti-proliferative and tissue hydration promoting effects, and can loosen the collagen structure. 3. Allantoin can promote wound healing and has the effect of promoting epithelial formation and increasing tissue hydration capacity. The three active ingredients of this product work synergistically to better inhibit fibroblast proliferation, especially to reduce pathological excessive collagen proliferation. 4. Based on current information, no mutagenic, teratogenic or carcinogenic effects have been found. |
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