Right kidney hypoplasia

We all know that normal people have two kidneys, one on each side of the body. Although the body can still circulate normally without one kidney, its resistance will be reduced, so we still have to learn to protect our bodies. Some patients often feel uncomfortable when urinating. When they go to the hospital for examination, they find that their right kidney is underdeveloped. So what exactly is the cause of right kidney underdevelopment?

Renal dysplasia is the clinical consequence of renal abnormalities, and its typical pathological histological features are the appearance of primitive glomeruli and tubules, chondroid metaplasia, etc.

Renal dysplasia is a congenital disorder in which the kidneys fail to grow and develop normally. Most are sporadic, and a few have a familial tendency. The extent of the disease depends on whether unilateral or bilateral kidneys are affected and which kidney's growth and differentiation stage is affected. This disease is one of the most common causes of abdominal masses in newborns. The lesions are often unilateral and are related to segmental stenosis of the renal collecting system. Bilateral lesions are often life-threatening. Most patients can be diagnosed by prenatal ultrasound, and the clinical manifestation is an asymptomatic abdominal mass. The affected kidney loses its normal shape and is replaced by an irregular cyst. The affected kidney is non-functional and often accompanied by ureteral obstruction. The contralateral kidney may have compensatory hypertrophy, and 10% also have contralateral urinary obstruction.

Abnormal development of renal blood vessels, renal tubules, collecting ducts and urinary drainage system can lead to renal parenchymal distortion and abnormal renal function. The diagnosis of renal hypoplasia may require a renal biopsy.

The cause of the disease is unclear, but it may be due to the influence of various external physical, chemical and toxic factors on the kidneys at a certain stage of growth and development. The important pathological feature is the discovery of primitive renal tubules surrounded by renal parenchymal tissue at different stages of differentiation. The tubular epithelial cells are cubic or columnar, sometimes ciliated, and are in an immature state. Primitive or fetal glomeruli and renal tubules may be found, showing chondroid metaplasia. Cysts originate from the collecting ducts or from the glomeruli. Their size and shape vary greatly and they may sometimes be absent. Kidney size depends on the stage of growth and development affected. Some renal dysplasia lesions are focal.

Depends on the extent of involvement. Complete renal dysplasia with bilateral kidney involvement often results in neonatal death. Unilateral involvement may be asymptomatic and only discovered incidentally in later years. The diseased kidney often has renal ectopia, such as

Located in the pelvic cavity, etc. The healthy kidney on the other side is prone to hydronephrosis, kidney stones and urinary tract infection. Some patients with renal dysplasia may be asymptomatic, but may occasionally present with giant ureters and giant cysts. The disease is often associated with other vascular developmental abnormalities.

Depends on the extent of involvement. Complete renal dysplasia with bilateral kidney involvement often results in neonatal death. Unilateral involvement may be asymptomatic and only discovered incidentally in later years. The diseased kidney often presents with renal ectopia, such as the kidney being located in the pelvic cavity. The healthy kidney on the other side is prone to hydronephrosis, kidney stones and urinary tract infection. Some patients with renal dysplasia may be asymptomatic, but may occasionally present with giant ureters and giant cysts. The disease is often associated with other vascular developmental abnormalities.